Department of Biological and Biomedical Sciences, Aga Khan University, Stadium Road, Karachi, Pakistan.
Exp Parasitol. 2012 Apr;130(4):311-3. doi: 10.1016/j.exppara.2012.01.021. Epub 2012 Feb 13.
Acanthamoeba hosts diverse microbial organisms including viruses, bacteria, yeast and protists, some of which are potential human pathogens. The precise nature of this symbiosis is not clear, but it is suggested that such interactions enable pathogenic microbes to survive hostile conditions and lead to their transmission to susceptible hosts to establish infection. In particular, Acanthamoeba-bacteria interactions have gained significant attention by the scientific and the medical community and have led to speculations of employing anti-amoebic approaches in eradicating 'superbugs' from clinical settings. Here, we discuss the nature of these convoluted interactions and the benefit they represent for the symbionts.
棘阿米巴宿主包含多种微生物，包括病毒、细菌、酵母和原生生物，其中一些是潜在的人类病原体。这种共生关系的确切性质尚不清楚，但有研究表明，这种相互作用使致病性微生物能够在恶劣环境中存活，并导致它们传播给易感宿主以建立感染。特别是，棘阿米巴与细菌的相互作用引起了科学界和医学界的高度关注，并促使人们推测可以采用抗阿米巴的方法从临床环境中根除“超级细菌”。在这里，我们讨论了这些复杂相互作用的性质及其对共生体的意义。
