Khan Naveed Ahmed, Siddiqui Ruqaiyyah
Department of Biological and Biomedical Sciences, Aga Khan University, Karachi, Pakistan.
Parasitology. 2014 Jun;141(7):869-74. doi: 10.1017/S003118201300231X. Epub 2014 Feb 5.
By interactions with other microbes, free-living amoebae play a significant role in microbiology, environmental biology, physiology, cellular interactions, ecology and evolution. Here, we discuss astonishing interactions of bacteria and amoebae, in the light of evolution and functional aspects impacting human health. In favourable environmental conditions, the interaction of Acanthamoeba with non-virulent bacteria results in lysis of the bacteria. However, the interaction with weak-virulent bacteria results in a symbiotic relationship or amoebal lysis may occur. The microbial survival of amoebae in harsh environments, ability to interact with bacteria, and their ability to aid transmission to susceptible hosts is of great concern to human, animal and ecosystem health.
通过与其他微生物的相互作用，自由生活的变形虫在微生物学、环境生物学、生理学、细胞相互作用、生态学和进化中发挥着重要作用。在此，我们根据影响人类健康的进化和功能方面，讨论细菌与变形虫之间惊人的相互作用。在有利的环境条件下，棘阿米巴与无毒细菌的相互作用会导致细菌裂解。然而，与弱毒细菌的相互作用会导致共生关系，或者可能发生阿米巴裂解。变形虫在恶劣环境中的微生物存活、与细菌相互作用的能力以及它们协助传播给易感宿主的能力，对人类、动物和生态系统健康至关重要。
