Department of Surgery, Kuopio University Hospital, Kuopio, Finland.
In Vivo. 2012 Mar-Apr;26(2):335-9.
Nonspecific abdominal pain is the commonest cause of a patient presenting to a doctor with abdominal pain of less than one week's duration. The differential diagnosis of NSAP is not always easy due to many similarities in the clinical presentation at onset and many cases may be misdiagnosed in the initial situation. To the Authors' knowledge, the diagnostic accuracy of history-taking is rarely considered in NSAP, and therefore the aim of the present study was to investigate the contribution of history-taking to correctly diagnosing NSAP in the clinical situation.
The accuracy of clinical diagnosis of NSAP was studied in connection with the survey of acute abdominal pain by the Research Committee of the World Organization of Gastroenterology (OMGE). In an extension of the OMGE acute abdominal pain study, 1333 patients presenting with acute abdominal pain were included in the study. The clinical symptoms of each patient were recorded in detail, using a predefined structured data collection sheet, and the collected data were compared with the final diagnosis of the patients.
The most significant symptoms of NSAP in univariate analysis were: vomiting (Usefulness Index, UI=0.11, Risk Ratio, RR=2.01), progression of pain (UI=0.10, RR=1.90), location of pain at diagnosis (UI=0.05, RR=1.75), intensity of pain (UI=0.05, RR=1.57) and previous indigestion (UI=0.05, RR=1.44). The sensitivity of the doctors' initial decision in detecting NSAP was 0.70, with a specificity of 0.83 and an efficiency of 0.77.
The results of this study do not support a specific link between any one clinical symptom and NSAP diagnosis. However, patients with midline pain, without any increase in pain and without vomiting, and those with weak or moderate pain tended to be at risk for NSAP.
非特异性腹痛是患者因腹痛就诊,且腹痛持续时间少于一周的最常见原因。由于在发病初期临床表现有许多相似之处,许多病例可能会被误诊,因此非特异性腹痛的鉴别诊断并不总是那么容易。据作者所知,病史采集在非特异性腹痛中的诊断准确性很少被考虑,因此本研究旨在调查病史采集在临床情况下正确诊断非特异性腹痛的作用。
世界胃肠病学组织(OMGE)急性腹痛研究委员会对非特异性腹痛的临床诊断准确性进行了研究。在 OMGE 急性腹痛研究的扩展中,共纳入了 1333 例出现急性腹痛的患者。每位患者的临床症状均使用预定义的结构化数据采集表详细记录,并将采集的数据与患者的最终诊断进行比较。
在单因素分析中,非特异性腹痛最显著的症状是:呕吐(有用性指数 UI=0.11,风险比 RR=2.01)、疼痛进展(UI=0.10,RR=1.90)、诊断时疼痛位置(UI=0.05,RR=1.75)、疼痛强度(UI=0.05,RR=1.57)和既往消化不良(UI=0.05,RR=1.44)。医生初步决策检测非特异性腹痛的敏感性为 0.70,特异性为 0.83,效率为 0.77。
本研究结果不支持任何单一临床症状与非特异性腹痛诊断之间存在特定联系。然而,中线疼痛、疼痛无加重且无呕吐、疼痛程度较弱或中等的患者,存在非特异性腹痛的风险。