Department of Surgery Kuopio University Hospital and School of Medicine, University of Eastern Finland, Kuopio, Finland.
Science Service Center, Kuopio University Hospital and School of Medicine, University of Eastern Finland, Kuopio, Finland.
In Vivo. 2021 Sep-Oct;35(5):2729-2738. doi: 10.21873/invivo.12557.
BACKGROUND/AIM: The diagnostic scores (DSs) for patients with non-specific abdominal pain (NSAP) have been rarely evaluated.
In the NSAP study group there were 614 patients (268 females and 346 males) versus 719 patients in the non-NSAP group including 368 females and 351 males. The clinical symptoms (n=22), signs and tests (n=14) and laboratory analyses (n=3) were recorded in each patient. Meta-analytical techniques were used to detect the summary sensitivity (Se) and specificity (Sp) estimates for each data set (symptoms, signs and tests as well as DS models).
In receiver operating characteristic (ROC) analysis, the area under curve (AUC) values for i) symptoms ii) signs and tests and iii) DS were as following: i) AUC=0.542 (95% CI=0.512-0.572); ii) AUC=0.625 (95% CI=0.550-0.700), and iii) AUC=0.874 (95% CI=0.850-0.898). The differences between these AUC values are as following: between i and ii, p=0.097; between i and iii, p<0.0001 and between ii and iii, p<0.0001.
This is the first study to provide evidence that DS may help in the difficult diagnosis of NSAP.
背景/目的：针对非特异性腹痛（NSAP）患者的诊断评分（DS）很少得到评估。
在 NSAP 研究组中，有 614 名患者（268 名女性和 346 名男性），而非 NSAP 组有 719 名患者，包括 368 名女性和 351 名男性。每位患者均记录了临床症状（n=22）、体征和检查（n=14）以及实验室分析（n=3）。使用荟萃分析技术检测每个数据集（症状、体征和检查以及 DS 模型）的汇总敏感性（Se）和特异性（Sp）估计值。
在受试者工作特征（ROC）分析中，i）症状、ii）体征和检查以及 iii）DS 的曲线下面积（AUC）值分别为：i）AUC=0.542（95%CI=0.512-0.572）；ii）AUC=0.625（95%CI=0.550-0.700），iii）AUC=0.874（95%CI=0.850-0.898）。这些 AUC 值之间的差异如下：i 与 ii 之间，p=0.097；i 与 iii 之间，p<0.0001；ii 与 iii 之间，p<0.0001。
这是第一项提供证据表明 DS 可能有助于诊断 NSAP 的困难诊断的研究。
