Dipartimento di Chimica G. Ciamician, Università di Bologna, V. F. Selmi 2, 40126 Bologna, Italy.
Chemistry. 2012 Apr 2;18(14):4308-13. doi: 10.1002/chem.201102703. Epub 2012 Feb 22.
Lysozyme has been successfully used to solvate carbon nanotubes (CNT). Extensive molecular dynamics simulations show that 1) a favorite site of adsorption exists, 2) the protein-tube interaction region is located far from the active site, 3) two protein helices act as a tweezer that grips the nanotube, 4) a localized protein re-arrangement hides the tube from the solvent, and 5) aminic and amidic moieties of lysozyme behave similarly to surfactants in the solvation of the tube.
溶菌酶已成功用于溶解碳纳米管（CNT）。广泛的分子动力学模拟表明：1）存在一个首选的吸附位置；2）蛋白质-管相互作用区域位于远离活性部位的位置；3）两个蛋白质螺旋充当夹子，夹住纳米管；4）局部的蛋白质重排将管隐藏在溶剂之外；5）溶菌酶的氨基和酰胺部分在管的溶解中表现得类似于表面活性剂。
