Department of Chemical Engineering, University of Massachusetts, Amherst, MA, USA.
Small. 2012 May 7;8(9):1320-5. doi: 10.1002/smll.201102221. Epub 2012 Feb 22.
Defects are known to underlie the mechanical properties of materials, especially so at the nanoscale. Using four compositionally identical DNA triangles, defect density is found to be inversely correlated with assembly efficiency and melting temperature. These findings are supported by a series of experiments with more complex DNA pyramids. Because they are naturally responsive to stresses, defects present an attractive opportunity as design elements for responsive DNA materials.
缺陷是材料力学性能的基础，尤其是在纳米尺度下。使用四个组成相同的 DNA 三角形，发现缺陷密度与组装效率和熔点成反比。这些发现得到了一系列更复杂的 DNA 金字塔实验的支持。由于它们对压力自然有响应，因此缺陷为响应性 DNA 材料的设计元素提供了一个有吸引力的机会。
