猪流行性腹泻病毒变异株的全基因组序列。
Complete genome sequence of a porcine epidemic diarrhea virus variant.
机构信息
Division of Swine Infectious Diseases, State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences,Harbin, People’s Republic of China.
出版信息
J Virol. 2012 Mar;86(6):3408. doi: 10.1128/JVI.07150-11.
Abstract
In 2011, outbreaks of viral diarrhea were observed on most swine-breeding farms in most of the provinces of China. The disease is characterized by vomiting, severe diarrhea, and a high mortality rate (82.3%) in newborn piglets. The clinical appearance was similar to that of porcine epidemic diarrhea virus (PEDV) infection. PEDVs were detected in samples (feces or small intestines) from most farms. In order to investigate whether there is a PEDV variant circulating in China, we sequenced and analyzed the complete genome of the recently identified field strain, CH/FJND-3/2011. The sequence data indicate that this PEDV variant prevails in China.
摘要
2011 年，中国大部分省份的大多数养猪场都爆发了病毒性腹泻。该病的特征是呕吐、严重腹泻和新生仔猪死亡率高（82.3%）。临床症状与猪流行性腹泻病毒（PEDV）感染相似。在大多数农场的样本（粪便或小肠）中都检测到了 PEDV。为了调查中国是否存在流行的 PEDV 变异株，我们对最近鉴定的田间分离株 CH/FJND-3/2011 的全基因组进行了测序和分析。序列数据表明，这种 PEDV 变异株在中国流行。
相似文献
1
Complete genome sequence of a porcine epidemic diarrhea virus variant.
J Virol. 2012 Mar;86(6):3408. doi: 10.1128/JVI.07150-11.
2
Characteristics of the spike and ORF3 genes of porcine epidemic diarrhea virus in Henan and Shanxi provinces of China.
Arch Virol. 2020 Oct;165(10):2323-2333. doi: 10.1007/s00705-020-04744-x. Epub 2020 Jul 26.
3
Molecular characterization and phylogenetic analysis of porcine epidemic diarrhea viruses associated with outbreaks of severe diarrhea in piglets in Jiangxi, China 2013.
PLoS One. 2015 Mar 19;10(3):e0120310. doi: 10.1371/journal.pone.0120310. eCollection 2015.
4
Complete genome sequence of a highly prevalent isolate of porcine epidemic diarrhea virus in South China.
J Virol. 2012 Sep;86(17):9551. doi: 10.1128/JVI.01455-12.
5
Prevalence and phylogenetic analysis of porcine diarrhea associated viruses in southern China from 2012 to 2018.
BMC Vet Res. 2019 Dec 27;15(1):470. doi: 10.1186/s12917-019-2212-2.
6
Epidemic and genetic characterization of porcine epidemic diarrhea virus strains circulating in the regions around Hunan, China, during 2017-2018.
Arch Virol. 2020 Apr;165(4):877-889. doi: 10.1007/s00705-020-04532-7. Epub 2020 Feb 13.
7
Molecular characteristics of a novel recombinant of porcine epidemic diarrhea virus.
Arch Virol. 2019 Apr;164(4):1199-1204. doi: 10.1007/s00705-019-04166-4. Epub 2019 Feb 6.
8
Molecular characteristics of the spike gene of porcine epidemic diarrhoea virus strains in Eastern China in 2016.
Virus Res. 2018 Mar 2;247:47-54. doi: 10.1016/j.virusres.2018.01.013. Epub 2018 Feb 3.
9
Isolation and identification of a variant subtype G 2b porcine epidemic diarrhea virus and S gene sequence characteristic.
Infect Genet Evol. 2019 Jul;71:82-90. doi: 10.1016/j.meegid.2019.03.015. Epub 2019 Mar 21.
10
Complete genome sequence of a variant porcine epidemic diarrhea virus strain isolated in China.
J Virol. 2012 Nov;86(22):12448. doi: 10.1128/JVI.02228-12.
引用本文的文献
1
A Porcine Epidemic Diarrhea Virus Isolated from a Sow Farm Vaccinated with CV777 Strain in Yinchuan, China: Characterization, Antigenicity, and Pathogenicity.
Transbound Emerg Dis. 2023 Mar 7;2023:7082352. doi: 10.1155/2023/7082352. eCollection 2023.
2
Development and Efficacy Evaluation of a Novel Nanoparticle-Based Hemagglutination Inhibition Assay for Serological Studies of Porcine Epidemic Diarrhea Virus.
Vet Sci. 2025 Feb 1;12(2):101. doi: 10.3390/vetsci12020101.
3
Field-deployable porcine epidemic diarrhea virus diagnostics utilizing CRISPR-Cas13a.
Virulence. 2024 Dec;15(1):2429022. doi: 10.1080/21505594.2024.2429022. Epub 2024 Nov 19.
4
Construction and Immunogenicity of a Recombinant Porcine Pseudorabies Virus (PRV) Expressing the Major Neutralizing Epitope Regions of S1 Protein of Variant PEDV.
Viruses. 2024 Oct 8;16(10):1580. doi: 10.3390/v16101580.
5
Phylogenetic Analysis of Porcine Epidemic Diarrhea Virus (PEDV) during 2020-2022 and Isolation of a Variant Recombinant PEDV Strain.
Int J Mol Sci. 2024 Oct 10;25(20):10878. doi: 10.3390/ijms252010878.
6
Isolation and characterization of a novel S1-gene insertion porcine epidemic diarrhea virus with low pathogenicity in newborn piglets.
Virulence. 2024 Dec;15(1):2397512. doi: 10.1080/21505594.2024.2397512. Epub 2024 Sep 16.
7
Intranasal delivery of a recombinant adenovirus vaccine encoding the PEDV COE elicits potent mucosal and systemic antibody responses in mice.
Microbiol Spectr. 2024 Oct 3;12(10):e0069224. doi: 10.1128/spectrum.00692-24. Epub 2024 Aug 15.
8
Epidemiological monitoring and genetic variation analysis of pathogens associated with porcine viral diarrhea in southern China from 2021 to 2023.
Front Microbiol. 2024 Mar 20;15:1303915. doi: 10.3389/fmicb.2024.1303915. eCollection 2024.
9
Porcine Epidemic Diarrhea Virus: Etiology, Epidemiology, Antigenicity, and Control Strategies in China.
Animals (Basel). 2024 Jan 17;14(2):294. doi: 10.3390/ani14020294.
10
Establishment and Application of a Triplex Real-Time RT-PCR Assay for Differentiation of PEDV, PoRV, and PDCoV.
Viruses. 2023 May 25;15(6):1238. doi: 10.3390/v15061238.
本文引用的文献
1
Complete genome sequence of a Chinese virulent porcine epidemic diarrhea virus strain.
J Virol. 2011 Nov;85(21):11538-9. doi: 10.1128/JVI.06024-11.
2
Heterogeneity in spike protein genes of porcine epidemic diarrhea viruses isolated in Korea.
Virus Res. 2010 May;149(2):175-82. doi: 10.1016/j.virusres.2010.01.015. Epub 2010 Feb 2.
3
Chinese-like strain of porcine epidemic diarrhea virus, Thailand.
Emerg Infect Dis. 2009 Jul;15(7):1112-5. doi: 10.3201/eid1507.081256.
4
Sequence analysis of the partial spike glycoprotein gene of porcine epidemic diarrhea viruses isolated in Korea.
Virus Genes. 2007 Oct;35(2):321-32. doi: 10.1007/s11262-007-0096-x. Epub 2007 Apr 11.
5
Completion of the porcine epidemic diarrhoea coronavirus (PEDV) genome sequence.
Virus Genes. 2001;23(2):137-44. doi: 10.1023/a:1011831902219.
Zotero 插件