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猪流行性腹泻病毒变异株的全基因组序列。

Complete genome sequence of a porcine epidemic diarrhea virus variant.

机构信息

Division of Swine Infectious Diseases, State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences,Harbin, People’s Republic of China.

出版信息

J Virol. 2012 Mar;86(6):3408. doi: 10.1128/JVI.07150-11.

DOI:10.1128/JVI.07150-11
PMID:22354946
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3302349/
Abstract

In 2011, outbreaks of viral diarrhea were observed on most swine-breeding farms in most of the provinces of China. The disease is characterized by vomiting, severe diarrhea, and a high mortality rate (82.3%) in newborn piglets. The clinical appearance was similar to that of porcine epidemic diarrhea virus (PEDV) infection. PEDVs were detected in samples (feces or small intestines) from most farms. In order to investigate whether there is a PEDV variant circulating in China, we sequenced and analyzed the complete genome of the recently identified field strain, CH/FJND-3/2011. The sequence data indicate that this PEDV variant prevails in China.

摘要

2011 年,中国大部分省份的大多数养猪场都爆发了病毒性腹泻。该病的特征是呕吐、严重腹泻和新生仔猪死亡率高(82.3%)。临床症状与猪流行性腹泻病毒(PEDV)感染相似。在大多数农场的样本(粪便或小肠)中都检测到了 PEDV。为了调查中国是否存在流行的 PEDV 变异株,我们对最近鉴定的田间分离株 CH/FJND-3/2011 的全基因组进行了测序和分析。序列数据表明,这种 PEDV 变异株在中国流行。

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本文引用的文献

1
Complete genome sequence of a Chinese virulent porcine epidemic diarrhea virus strain.一株中国强毒猪流行性腹泻病毒的全基因组序列。
J Virol. 2011 Nov;85(21):11538-9. doi: 10.1128/JVI.06024-11.
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