Chukwuka Ugwu Anthony, Kalu Agwu Kenneth, Erondu Okechukwu Felix
Department of Radiography and Radiological sciences Nnamdi Azikiwe University, Nnewi Campus, Anambra State, Nigeria.
Pan Afr Med J. 2011;9:11. doi: 10.4314/pamj.v9i1.71186. Epub 2011 May 31.
The objective of this study was to assess the variabilities of gallbladder contraction indices (GBCI) and derive a predictive model for gallbladder and gastric motility.
The gallbladder volume and gastric antral measurements were obtained from 24 healthy male volunteers in preprandial and post-milk ingestion states. After preprandial measurement of the gallbladder volume and gastric antral area, each subject ingested 157 ml of full cream milk and 30 cl of ion-free water. In supine position, the gallbladder volume and the gastric antral area were obtained every five minutes for 40 minutes. For the gallbladder while only the 5(th), 10(th) and 15(th) measurement of gastric antral area were obtained. Gallbladder contraction indices were calculated and gastric emptying ratio obtained at the fifteenth minute is the indication of gastric motility. Statistical analyses were conducted using SPSS version 16.0 with p < 0.05 as criterion of statistical significance.
The GBCIs followed Gaussian response at some stages and did not at some other stages. The least variability occurred at the 35th measurement of GBCI. A cut- off value for the 35th minute GBCI value was established with the mean ± 2 SD (80.79 ± 11.5%). Obvious gallbladder refilling was noted after 35 minutes. A positive relationship was noted between gallbladder and gastric motilities.
With milk dilution, the variability of gall bladder motility is least at the 35th minute. A significant positive relationship between gastric emptying and gallbladder contraction index was also observed.
本研究的目的是评估胆囊收缩指数（GBCI）的变异性，并推导胆囊和胃动力的预测模型。
从24名健康男性志愿者在空腹和摄入牛奶后的状态下获取胆囊体积和胃窦测量值。在空腹测量胆囊体积和胃窦面积后，每位受试者摄入157毫升全脂牛奶和30厘升无离子水。受试者仰卧位，每隔5分钟测量一次胆囊体积和胃窦面积，共测量40分钟。对于胆囊，仅获取第5、10和15分钟时的胃窦面积测量值。计算胆囊收缩指数，以第15分钟时获得的胃排空率作为胃动力的指标。使用SPSS 16.0进行统计分析，以p < 0.05作为统计学显著性标准。
GBCI在某些阶段呈高斯反应，而在其他阶段则不然。GBCI在第35次测量时变异性最小。以均值±2标准差（80.79±11.5%）确定了第35分钟GBCI值的临界值。35分钟后观察到明显的胆囊再充盈。胆囊和胃动力之间存在正相关关系。
在牛奶稀释的情况下，胆囊动力在第35分钟时变异性最小。还观察到胃排空与胆囊收缩指数之间存在显著正相关关系。
