Glasbrenner B, Pieramico O, Holzwarth C, Malfertheiner P
Abt. Innere Medizin II, Universität Ulm.
Bildgebung. 1992 Jun;59(2):88-93.
Postprandial gastric emptying and gallbladder contraction were assessed in 14 healthy subjects by means of ultrasonography after oral administration of a semi-liquid test meal (250 ml, 1450 kJ). For this purpose, cross-sectional areas of the gastric antrum and gallbladder volume were calculated and recorded over a period of 120 minutes using an annular-array-transducer. The semi-liquid test meal allowed suitable sonographic measurement of cross-sectional areas of the antrum in all 14 subjects. Mean half-time of gastric emptying was 47 minutes (range 17-72 minutes). Mean peak gallbladder contraction was 36% (range 17-60%) of initial volume and mean time to peak contraction was 65 minutes (range 20-120 minutes). The method described was found to be a practical and reliable procedure for the investigation of postprandial gastric emptying and gallbladder contraction. It is therefore of potential interest for application to a variety of clinical questions. A minor drawback involves the relative length and variability of time required for testing, owing to the wide range in the time-course of gastric emptying and gallbladder contraction across subjects. Normal ranges for defined test meals must be established in large control groups.
在14名健康受试者口服半流质试验餐(250毫升,1450千焦)后,通过超声检查评估餐后胃排空和胆囊收缩情况。为此,使用环形阵列换能器在120分钟内计算并记录胃窦的横截面积和胆囊容积。半流质试验餐使所有14名受试者的胃窦横截面积都能进行合适的超声测量。胃排空的平均半衰期为47分钟(范围17 - 72分钟)。胆囊收缩的平均峰值为初始容积的36%(范围17 - 60%),达到峰值收缩的平均时间为65分钟(范围20 - 120分钟)。所描述的方法被发现是一种用于研究餐后胃排空和胆囊收缩的实用且可靠的程序。因此,它对于应用于各种临床问题具有潜在的意义。一个小缺点是由于不同受试者胃排空和胆囊收缩的时间进程范围广泛,测试所需时间相对较长且存在变异性。必须在大型对照组中建立特定试验餐的正常范围。