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淋巴瘤、胸腺瘤和木人:胸腺瘤切除术后和非霍奇金淋巴瘤缓解后的僵人综合征。

Lymphoma, thymoma and the wooden man: stiff-person syndrome post-thymoma excision and non-Hodgkin lymphoma remission.

机构信息

Prince of Wales Hospital, Sydney, Australia.

出版信息

Intern Med J. 2012 Feb;42(2):205-7. doi: 10.1111/j.1445-5994.2011.02688.x.

DOI:10.1111/j.1445-5994.2011.02688.x
PMID:22356495
Abstract

Stiff-person syndrome (SPS) is an uncommon yet under-diagnosed, neuromuscular disorder characterised by progressive muscle rigidity with superimposed painful muscle spasms triggered by tactile, auditory or emotional stimulation. We describe the world's first case report of typical SPS in a patient with previously excised thymoma and treated non-Hodgkin lymphoma. This is of relevance because of the increasingly elucidated autoimmune aetiology of SPS.

摘要

僵人综合征(SPS)是一种罕见但未被充分诊断的神经肌肉疾病,其特征是进行性肌肉僵硬,伴有由触觉、听觉或情绪刺激引发的疼痛性肌肉痉挛。我们描述了首例先前切除胸腺瘤和治疗非霍奇金淋巴瘤的患者中出现典型 SPS 的病例报告。这是相关的,因为 SPS 的自身免疫病因学越来越明确。

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Lymphoma, thymoma and the wooden man: stiff-person syndrome post-thymoma excision and non-Hodgkin lymphoma remission.淋巴瘤、胸腺瘤和木人:胸腺瘤切除术后和非霍奇金淋巴瘤缓解后的僵人综合征。
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Advances in Autoimmune Epilepsy Associated with Antibodies, Their Potential Pathogenic Molecular Mechanisms, and Current Recommended Immunotherapies.自身免疫性癫痫与抗体相关的研究进展、潜在致病分子机制及当前推荐的免疫疗法
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