Prince of Wales Hospital, Sydney, Australia.
Intern Med J. 2012 Feb;42(2):205-7. doi: 10.1111/j.1445-5994.2011.02688.x.
Stiff-person syndrome (SPS) is an uncommon yet under-diagnosed, neuromuscular disorder characterised by progressive muscle rigidity with superimposed painful muscle spasms triggered by tactile, auditory or emotional stimulation. We describe the world's first case report of typical SPS in a patient with previously excised thymoma and treated non-Hodgkin lymphoma. This is of relevance because of the increasingly elucidated autoimmune aetiology of SPS.
僵人综合征(SPS)是一种罕见但未被充分诊断的神经肌肉疾病,其特征是进行性肌肉僵硬,伴有由触觉、听觉或情绪刺激引发的疼痛性肌肉痉挛。我们描述了首例先前切除胸腺瘤和治疗非霍奇金淋巴瘤的患者中出现典型 SPS 的病例报告。这是相关的,因为 SPS 的自身免疫病因学越来越明确。