Dilworth J P, Neal D E, Fussell E N, Roberts J A
Department of Urology, Delta Regional Primate Research Center, Covington, Louisiana 70433.
Prostate. 1990;17(3):227-31. doi: 10.1002/pros.2990170306.
Both man and monkey possess urothelial (transitional cell) receptors for P-fimbriae of Escherichia coli; however, the male urethra has pseudostratified columnar cells. We studied adherence using scanning electron microscopy and found that P-fimbriae were the principal mediators of adherence to these cells as well. The monkey, therefore, should be a good model for the study of the ascending route of infection in prostatitis, the route thought to occur in man.
人类和猴子都拥有大肠杆菌P菌毛的尿路上皮（移行细胞）受体；然而，男性尿道有假复层柱状细胞。我们使用扫描电子显微镜研究了黏附情况，发现P菌毛也是这些细胞黏附的主要介质。因此，猴子应该是研究前列腺炎感染上行途径的良好模型，这种途径被认为也发生在人类身上。
