Experimental bacterial prostatitis in dogs.

Bacterial prostatitis was successfully induced in 30 dogs by the injection of E. coli into a branch of a prostatic artery. Inflammation was proven histologically in all cases and by the appearance of E. coli in the prostatic secretion in all but two dogs. In these two dogs cultures from prostatic tissue were positive for E. coli. The pH changes in the prostatic secretion were inconclusive, and the zinc levels increased slightly in the acutely inflamed gland. Antibody coating of the bacteria could not be demonstrated by immunofluorescence.