Yang Yan, Yu Shan-fa, Jiang Kai-you
Henan Institute of Occupational Health, Zhengzhou 450052, China.
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2011 Dec;29(12):898-901.
To explore the relationship between occupational stress and serum glycosylated hemoglobin A1c (HbA1c) level.
A cross-sectional epidemiological study was conducted in 115 dispatchers. The occupational stressors, personality, occupational strain and coping with stress were measured using Occupational Stress Instrument. Serum HbA1c levels were measured by stratigraphic analysis of cation exchange resin.
Serum HbA1c level (6.63% ± 1.93%) in the shiftwork group was significantly higher than that (5.73% ± 1.57%) in the daily relay work group (P < 0.05). Spearman correlation analyses showed the positive correlation between type A behavior and serum HbA1c level (r = 0.221), the negative correlation between organizational commitment and serum HbA1c level (r = -0.218). Variance analyses revealed that serum HbA1c levels among high, middle and low job requirement groups and job control groups were significantly different (P < 0.05). There were significant differences of serum HbA1c levels among different type A behavior, internal control, susceptibility of stress and organizational commitment groups (P < 0.05). Stepwise regression analyses indicated that shiftwork affects obviously serum HbAlc level, internal control and job future were the predictors of serum HbA1c level (R2 = 0.082).
Serum HbA1c may be a potential biomarker in field investigation of the effects of occupational stress.
探讨职业压力与血清糖化血红蛋白A1c（HbA1c）水平之间的关系。
对115名调度员进行横断面流行病学研究。使用职业压力量表测量职业压力源、个性、职业紧张和应对压力的情况。采用阳离子交换树脂分层分析法测定血清HbA1c水平。
轮班工作组的血清HbA1c水平（6.63%±1.93%）显著高于日常轮值工作组（5.73%±1.57%）（P<0.05）。Spearman相关性分析显示，A型行为与血清HbA1c水平呈正相关（r=0.221），组织承诺与血清HbA1c水平呈负相关（r=-0.218）。方差分析显示，高、中、低工作要求组和工作控制组之间的血清HbA1c水平存在显著差异（P<0.05）。不同A型行为、内部控制、压力易感性和组织承诺组之间的血清HbA1c水平存在显著差异（P<0.05）。逐步回归分析表明，轮班工作对血清HbAlc水平有明显影响，内部控制和职业前景是血清HbA1c水平的预测因素（R2=0.082）。
血清HbA1c可能是职业压力影响现场调查中的一个潜在生物标志物。
