Ohlmann C-H, Siemer S, Stöckle M
Klinik für Urologie und Kinderurologie, Universitätsklinikum des Saarlandes, Kirrbergerstraße 1, Gebäude 6, 66421 Homburg/Saar, Deutschland.
Urologe A. 2012 Mar;51(3):363-7. doi: 10.1007/s00120-012-2827-4.
Surgical resection of a solitary or a limited number of metastases is a controversy in patients with prostate cancer that is increasingly being discussed. The improved accuracy of the detection of local or distant recurrences after primary treatment using modern imaging techniques including choline PET/CT led to an increased demand for salvage surgical procedures. Apart from the resection of synchronous metastases at the time of radical prostatectomy the oncological efficacy of a salvage lymphadenectomy or a salvage resection of visceral or osseous metastases remains to be proven. Here, the available data covering the different clinical scenarios for the resection of metastases in prostate cancer and recommendations of recently published guidelines are reviewed.
对于前列腺癌患者，手术切除单个或有限数量的转移灶存在争议，且这一争议正日益受到讨论。使用包括胆碱PET/CT在内的现代成像技术，可提高原发治疗后局部或远处复发检测的准确性，这导致对挽救性手术的需求增加。除了在根治性前列腺切除术时切除同步转移灶外，挽救性淋巴结清扫术或内脏或骨转移灶的挽救性切除术的肿瘤学疗效仍有待证实。在此，我们回顾了涵盖前列腺癌转移灶切除不同临床情况的现有数据以及最近发表的指南建议。
