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剥脱性骨软骨炎知识回顾:从 König 到 ROCK 研究组,123 年的微小演变。

A review of knowledge in osteochondritis dissecans: 123 years of minimal evolution from König to the ROCK study group.

机构信息

Rady Children's Hospital and Health Center, 3030 Children's Way, Suite 410, San Diego, CA 92123, USA.

出版信息

Clin Orthop Relat Res. 2013 Apr;471(4):1118-26. doi: 10.1007/s11999-012-2290-y.

Abstract

BACKGROUND

Osteochondritis dissecans (OCD) was first described to provide an explanation for the nontraumatic development of loose bodies within a joint. Despite many reports on the subject, there remains no clear understanding of the etiology, natural history, or treatment.

QUESTIONS/PURPOSES: This review was undertaken to delineate (1) the etiology of OCD; (2) the presentation and locations; (3) the most appropriate imaging modalities; and (4) the most effective treatment strategies.

METHODS

We reviewed the English literature using a database compiled from a Medline search for "osteochondritis dissecans". We identified 1716 publications, 1246 of which were in English. After exclusions, we reviewed 748 articles and of these cited 85. The observations of each study were then synthesized into this report.

RESULTS

There appears to be no consensus concerning the etiology of OCD lesions. The presentations and locations are variable, but the knee, ankle, and elbow are most commonly involved. Although plain film assessment is important in OCD, there appears to be a trend toward the use of MRI, but the preferred sequences are in evolution. We found no consensus on the treatment of these lesions, related in part to the lack of agreement of methods for assessing outcomes.

CONCLUSIONS

Despite more than a century of study, we have made little advancement in our understanding of OCD. A study group has been formed to address this issue and actively seeks to answer these unknown issues regarding OCD.

摘要

背景

剥脱性骨软骨炎(OCD)最初被描述为关节内非创伤性游离体形成的解释。尽管有很多关于这个主题的报告,但对于病因、自然史或治疗方法仍没有明确的理解。

问题/目的:本次综述旨在描述:(1)OCD 的病因;(2)临床表现和位置;(3)最合适的影像学检查方法;以及(4)最有效的治疗策略。

方法

我们使用从 Medline 搜索“osteochondritis dissecans”中编译的数据库,对英文文献进行了综述。我们共找到了 1716 篇出版物,其中 1246 篇是英文的。经过排除,我们共回顾了 748 篇文章,并引用了其中的 85 篇。然后将每个研究的观察结果综合到这份报告中。

结果

关于 OCD 病变的病因似乎没有共识。临床表现和位置各不相同,但膝关节、踝关节和肘关节最常受累。尽管平片评估在 OCD 中很重要,但似乎有使用 MRI 的趋势,但首选序列仍在发展中。我们发现这些病变的治疗方法没有共识,这部分与评估结果的方法缺乏一致性有关。

结论

尽管已经研究了一个多世纪,但我们对 OCD 的理解几乎没有进展。已经成立了一个研究小组来解决这个问题,并积极寻求回答 OCD 相关的这些未知问题。

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