Oladeinde Bankole Henry, Phil Richard Omoregie M, Olley Mitsan, Anunibe Joshua A
Department of Medical Microbiology, College of Health Sciences, Igbinedion University, Edo State, Nigeria.
N Am J Med Sci. 2011 Dec;3(12):548-51. doi: 10.4297/najms.2011.3548.
Human immunodeficiency virus (HIV) prevalence is high among rural dwellers and pregnant women.
This study aims to determine the prevalence of HIV and anemia among pregnant women attending antenatal clinic in rural community of Okada, Edo State, Nigeria.
Anticoagulated blood and sera samples were obtained from 480 women consisting of 292 pregnant and 188 non-pregnant women. Antibodies to HIV were detected in the sera samples and hemoglobin concentration of the anticoagulated blood specimens were determined using standard techniques. Anemia was defined as hemoglobin concentration <11g/dl for pregnant women and <12g/dl for non-pregnant women.
Pregnancy was not a risk factor for acquiring HIV infection (pregnant vs. non-pregnant: 10.2% vs. 13.8%; OR=0.713, 95% CI=0.407, 1.259, P = 0.247). The prevalence of HIV was significantly (P = 0.005 and P = 0.025) higher in the age group 10-20 years and 21 - 30 years among pregnant and non-pregnant women respectively. Pregnancy was a risk factor for acquiring anemia (OR=1.717, 95% CI=1.179, 2.500, P = 0.006). Only the age of pregnant women significantly (P = 0.004) affected the prevalence of anemia inversely.
The prevalence of HIV and anemia among pregnant women were 10.2% and 49.3% respectively. Pregnancy was associated with anemia. Interventions by appropriate agencies are advocated to reduce associated sequelae.
人类免疫缺陷病毒(HIV)在农村居民和孕妇中的流行率很高。
本研究旨在确定尼日利亚江户州奥卡达农村社区产前诊所就诊孕妇中HIV和贫血的流行率。
从480名女性中采集抗凝血液和血清样本,其中包括292名孕妇和188名非孕妇。在血清样本中检测HIV抗体,并使用标准技术测定抗凝血液标本的血红蛋白浓度。贫血定义为孕妇血红蛋白浓度<11g/dl,非孕妇血红蛋白浓度<12g/dl。
怀孕不是感染HIV的危险因素(孕妇与非孕妇:10.2%对13.8%;OR=0.713,95%CI=0.407,1.259,P = 0.247)。在孕妇和非孕妇中,10 - 20岁年龄组和21 - 30岁年龄组的HIV流行率分别显著更高(P = 0.005和P = 0.025)。怀孕是患贫血的危险因素(OR=1.717,95%CI=1.179,2.500,P = 0.006)。只有孕妇年龄对贫血流行率有显著的反向影响(P = 0.004)。
孕妇中HIV和贫血的流行率分别为10.2%和49.3%。怀孕与贫血有关。提倡相关机构进行干预以减少相关后遗症。