Azadi Niloofar, Fallahdoost Arzhang, Mehrvarzfar Payman, Rakhshan Hamid, Rakhshan Vahid
Department of Public Health and Clinical Medicine, Umeå International School of Public Health, Epidemiology and Global Health, Umeå, Sweden.
Dent Res J (Isfahan). 2012 Jan;9(1):31-5. doi: 10.4103/1735-3327.92924.
The strong link between sealer solubility and periapical reinfection indicates that water solubility of new sealers should be studied. This study aimed to assess the water solubility of five root canal sealers (AH-26, Topseal, 2-Seal, Acroseal, and Roeko Seal Automix [RSA]).
In this in vitro experimental study, 30 specimens were fabricated from each of the abovementioned sealants. Then they were weighed and randomly divided into three subgroups of 10 each (A, B, and C). They were set at 37°C and 100% RH, in accordance with ANSI/ADA 57 and ISO 6876-2001 requirements. Afterward, the specimens in subgroups A were incubated at 37°C and 100% RH for 24 hours, while the specimens in the subgroups B and C were incubated in the same conditions for 7 days and 28 days, respectively. After incubation, the specimens were dried with blotting paper and were incubated for 24 hours at 37°C and 0% RH. Then they were weighed. The percentage of weight loss was regarded as water solubility.
The mean solubility of the sealers AH-26, Acroseal, Topseal, 2-Seal, and RSA were 0.28%, 0.36%, 0.07%, 0.037%, and 0.141% after 24 hours, respectively. After 28 days, their solubility were 1.75%, 0.746%, 0.082%, 0.04%, and 0.517%, respectively. Only the solubility of the sealers 2-Seal and Topseal were not statistically different (P>0.3 [Tukey's]). Again only the solubility of 2-Seal and Topseal did not significantly increase between the 7(th) day and the 28(th) day of incubation (P>0.6 [paired-samples t]).
All tested materials met the standards (maximum weight loss of 3% within 24 hours). However, the results of 2-Seal followed by Topseal were the most favorable ones.
封闭剂溶解度与根尖周再感染之间的紧密联系表明，应研究新型封闭剂的水溶性。本研究旨在评估五种根管封闭剂（AH-26、Topseal、2-Seal、Acroseal和Roeko Seal Automix [RSA]）的水溶性。
在这项体外实验研究中，从上述每种封闭剂制备30个样本。然后对它们进行称重，并随机分为三个亚组，每组10个（A、B和C）。根据ANSI/ADA 57和ISO 6876-2001要求，将它们置于37°C和100%相对湿度环境中。之后，A亚组的样本在37°C和100%相对湿度下孵育24小时，而B亚组和C亚组的样本分别在相同条件下孵育7天和28天。孵育后，用吸水纸将样本擦干，并在37°C和0%相对湿度下孵育24小时。然后对它们进行称重。重量损失百分比被视为水溶性。
24小时后，AH-26、Acroseal、Topseal、2-Seal和RSA封闭剂的平均溶解度分别为0.28%、0.36%、0.07%、0.037%和0.141%。28天后，它们的溶解度分别为1.75%、0.746%、0.082%、0.04%和0.517%。只有2-Seal和Topseal封闭剂的溶解度在统计学上无差异（P>0.3 [Tukey检验]）。同样，只有2-Seal和Topseal封闭剂的溶解度在孵育第7天和第28天之间没有显著增加（P>0.6 [配对样本t检验]）。
所有测试材料均符合标准（24小时内最大重量损失为3%）。然而，2-Seal其次是Topseal的结果是最有利的。
