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兔子作为实验研究的动物模型。

Rabbit as an animal model for experimental research.

作者信息

Mapara Manjeet, Thomas Betsy Sara, Bhat K M

机构信息

Department of Periodontics, MGM Dental College and Hospital, Navi Mumbai, India.

出版信息

Dent Res J (Isfahan). 2012 Jan;9(1):111-8. doi: 10.4103/1735-3327.92960.

DOI:10.4103/1735-3327.92960
PMID:22363373
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3283968/
Abstract

Animal experimentation is carried out in consultation with the veterinary wing but it is essential that be familiar with experimental protocols of animal model to be able to design an approriate study. This is more so in place where the veterinary facilities are not easily available.Span Rabbits are commonly used as subjects for screening implant material. They have gained favour for their numerous advantages even though they should be ideally used prior to testing in a larger animal model. Though experimentation on rabbits seems to be easy there are many pitfalls. Our endeavor in this article is to integrate all the data about maintaining rabbits as a model and to critically analyze it on the basis of our experimentation.

摘要

动物实验是在与兽医部门协商后进行的,但熟悉动物模型的实验方案对于设计合适的研究至关重要。在兽医设施不易获得的地方更是如此。西班牙兔通常被用作筛选植入材料的实验对象。尽管理想情况下应在更大的动物模型中进行测试之前使用它们,但它们因其众多优点而受到青睐。虽然对兔子进行实验似乎很容易,但也有许多陷阱。我们在本文中的努力是整合所有关于将兔子作为模型进行饲养的数据,并根据我们的实验对其进行批判性分析。

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Genome Res. 2007 Dec;17(12):1797-808. doi: 10.1101/gr.6761107. Epub 2007 Nov 5.
3
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Vet Med Sci. 2025 Jul;11(4):e70505. doi: 10.1002/vms3.70505.
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J Mater Sci Mater Med. 2025 Jul 8;36(1):58. doi: 10.1007/s10856-025-06908-0.
6
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Sci Rep. 2025 Jul 2;15(1):23159. doi: 10.1038/s41598-025-99582-9.
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6
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10
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