角膜生物力学特性对气动眼压计与压平眼压计眼压差值的影响。

Influence of corneal biomechanical properties on intraocular pressure differences between an air-puff tonometer and the Goldmann applanation tonometer.

机构信息

Dipartimento di Biopatologia e Diagnostica per Immagini, Sezione Oculistica, Università degli Studi Tor Vergata, Rome, Italy.

出版信息

J Glaucoma. 2013 Jun-Jul;22(5):416-21. doi: 10.1097/IJG.0b013e31824cafc9.

DOI:10.1097/IJG.0b013e31824cafc9

PMID:22366703

Abstract

PURPOSE

To estimate the influence of corneal properties on intraocular pressure (IOP) differences between an air-puff tonometer (NT530P; Nidek) and the Goldmann applanation tonometer (Haag-Streit).

PATIENTS AND METHODS

The influence of central corneal thickness (CCT), keratometry, and Ocular Response Analyzer (Reichert) measurements of corneal viscoelasticity [corneal hysteresis (CH) and corneal resistance factor (CRF)] on IOP differences between tonometers was evaluated.

RESULTS

The CRF was calculated to be the best predictor of the differences in IOP readings between tonometers (r2=0.23; P<0.001), followed by CCT (r2=0.15; P=0.003) and CH (r2=0.14; P=0.003). Keratometry performed very poorly as lone predictor of IOP differences. In a multiple regression model, CRF, CH, and CCT together accounted for 25% (r2=0.25; P<0.01) of the variance in IOP reading differences between tonometers.

CONCLUSIONS

Corneal resistance to applanation induced by either contact or noncontact tonometers was calculated to be the most determinant factor in influencing IOP differences between applanation tonometers.

摘要

目的

评估角膜特性对非接触式眼压计（NT530P；尼德克）和压平眼压计（Haag-Streit）之间眼压差异的影响。

方法

评估中央角膜厚度（CCT）、角膜曲率计和眼反应分析仪（Reichert）测量的角膜粘弹特性[角膜滞后（CH）和角膜阻力因子（CRF）]对眼压计之间眼压差异的影响。

结果

CRF 被计算为眼压计读数差异的最佳预测因子（r2=0.23；P<0.001），其次是 CCT（r2=0.15；P=0.003）和 CH（r2=0.14；P=0.003）。角膜曲率计作为眼压差异的唯一预测因子表现不佳。在多元回归模型中，CRF、CH 和 CCT 共同解释了眼压计之间眼压读数差异的 25%（r2=0.25；P<0.01）。