Department of Ophthalmology, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria Hospital Clínico San Carlos (IdISSC), Universidad Complutense, 28040, Madrid, Spain.
Alberto Hurtado School of Medicine, Peruana Cayetano Heredia University, Lima, Perú.
Int Ophthalmol. 2023 Nov;43(11):4121-4129. doi: 10.1007/s10792-023-02814-y. Epub 2023 Aug 26.
To compare intraocular pressure (IOP) measurements between Easyton transpalpebral tonometry and Perkins, iCare iC100 and Corvis ST. Also, to assess the influence of corneal characteristics and anterior scleral thickness (AST) on the IOP measurements.
Sixty-nine eyes from 69 healthy subjects were included. IOP was measured by Easyton, Perkins, iC100 and Corvis ST (corrected IOP, bIOP; and non-corrected IOP, IOPnct). Other variables studied were AST, axial length (AL), and Corvis parameters: Length 1, velocity 1, length 2, velocity 2, peak distance, radius, deformation amplitude, and central corneal thickness (CCT). Pearson correlation, limits of agreement (LoA), and multiple regression analysis were calculated.
No significant differences in IOP between Easyton and Perkins, iC100, and bIOP were observed (all p > 0.05), being significant only between Perkins and IOPnct ( - 1.49 mmHg, p < 0.001). Bland-Altman graphs showed that the mean difference between Perkins and Easyton was 0.07 mmHg (p < 0.001), and LoA - 7.49 to + 7.39 mmHg. Significant correlations were found between the measurements of Perkins and iC100, IOPnct, bIOP (r = 0.710, 0.628, 0.539; p < 0.001 respectively), iC100 and IOPnct, bIOP (r = 0.627, 0.513; p < 0.001, respectively). The multivariate regression analysis revealed that differences between Perkins and Easyton (adjusted R = 0.25) were influenced by AL (B = 1.28, p < 0.008), length 1 (B = 3.13, p < 0.018), and the radius (B = 1.26, p < 0.010). Differences between Perkins and bIOP (adjusted R = 0.21) were affected by the CCT (B = 0.029, p < 0.003).
There are no significant differences in the IOP measurements between Perkins and Easyton, iC100 or bIOP. Length 1, radius, and CCT have limited influence on these differences, while AST did not show any effect.
比较 Easyton 经皮眼压测量仪与 Perkins、iCare iC100 和 Corvis ST 的眼压测量值。同时,评估角膜特征和巩膜前厚度(AST)对眼压测量值的影响。
纳入 69 名健康受试者的 69 只眼。通过 Easyton、 Perkins、iC100 和 Corvis ST 测量眼压(校正眼压,bIOP;非校正眼压,IOPnct)。研究的其他变量包括 AST、眼轴(AL)和 Corvis 参数:长度 1、速度 1、长度 2、速度 2、峰距、半径、变形幅度和中央角膜厚度(CCT)。计算 Pearson 相关、界限(LoA)和多元回归分析。
Easyton 与 Perkins、iC100 和 bIOP 之间的眼压无显著差异(均 p>0.05),仅 Perkins 与 IOPnct 之间存在显著差异(-1.49mmHg,p<0.001)。Bland-Altman 图显示 Perkins 与 Easyton 之间的平均差值为 0.07mmHg(p<0.001),LoA 为-7.49 至+7.39mmHg。Perkins 与 iC100、IOPnct、bIOP 之间存在显著相关性(r=0.710、0.628、0.539;p<0.001)。多元回归分析显示, Perkins 与 Easyton 之间的差异(调整后的 R2=0.25)受 AL(B=1.28,p<0.008)、长度 1(B=3.13,p<0.018)和半径(B=1.26,p<0.010)的影响。Perkins 与 bIOP 之间的差异(调整后的 R2=0.21)受 CCT(B=0.029,p<0.003)的影响。
Perkins 与 Easyton、iC100 或 bIOP 的眼压测量值无显著差异。长度 1、半径和 CCT 对这些差异的影响有限,而 AST 则没有影响。