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腹腔镜和剖腹手术治疗子宫内膜癌:全面综述。

Laparoscopic and laparotomic approaches for endometrial cancer treatment: a comprehensive review.

机构信息

Department of Obstetrics and Gynecology, University of Saarland, Homburg, Saar, Germany.

出版信息

Arch Gynecol Obstet. 2012 Jul;286(1):167-72. doi: 10.1007/s00404-012-2254-1. Epub 2012 Feb 25.

DOI:10.1007/s00404-012-2254-1
PMID:22366805
Abstract

OBJECTIVE

Endometrial cancer (EC) is the most common gynecological malignancy in the developed world, particularly among postmenopausal women. Endoscopic surgery is gaining more popularity among surgeons as a safe and feasible option for treatment of endometrial carcinoma, providing the possibility of adequate lymph node excision.

METHODS

A comprehensive review.

RESULTS

The advantages of laparoscopy prevail over laparotomy and authors report lower peri-operative complication rates, less blood loss, lower transfusion rates, and shorter hospital stay, as well as a better quality of life (QoL) after laparoscopic surgery, in contrast to conventional abdominal surgery. This was confirmed by a meta-analysis of four randomized controlled studies. This is also true for obese risky patients to whom laparotomies carry indolent side effects. In addition, with more training and experience this procedure would be even more feasible and safer.

CONCLUSIONS

Because of the increasing importance of economic efficiency in health care, the endoscopic approach will continue to play a more important role in the future treatment of EC providing a better treatment option for the coming patients. As a promising therapeutical option, it should be offered to all patients with an early-stage EC.

摘要

目的

子宫内膜癌(EC)是发达国家最常见的妇科恶性肿瘤,尤其多见于绝经后妇女。内镜手术作为一种安全可行的子宫内膜癌治疗方法,为充分进行淋巴结切除提供了可能,越来越受到外科医生的青睐。

方法

全面复习。

结果

腹腔镜的优势超过了剖腹手术,与传统的腹部手术相比,作者报告腹腔镜手术具有更低的围手术期并发症发生率、更少的出血量、更低的输血率和更短的住院时间,以及更好的生活质量(QoL)。这一点也被四项随机对照研究的荟萃分析所证实。对于肥胖高危患者,剖腹手术也存在惰性副作用,这同样适用于腹腔镜手术。此外,随着更多的培训和经验,该手术将更加可行和安全。

结论

由于医疗保健中经济效益的重要性日益增加,内镜方法在未来 EC 的治疗中将继续发挥更重要的作用,为未来的患者提供更好的治疗选择。作为一种有前途的治疗选择,它应该提供给所有早期 EC 患者。

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