Perevoshchikova K A, Prokoph H, Hering B, Koen Ia M, Zbarskiĭ I B
Biull Eksp Biol Med. 1979 Jun;87(6):542-4.
Effects of heparin, spermidine, and Be2+ ions on the ATPase and beta-glycerophosphatase and RNA-ase activities of the rat liver cell nuclei were studied. Be2+ was shown to inhibit the ATPase activity and, to a lesser extent, beta-glycerophosphatase activities. Physiological concentrations of heparin and spermidine also lowered the mentioned two activities, as well as the RNAase activity of the nuclei. Evidence is presented for the inhibitory effect of heparin and spermidine on endonucleases.
研究了肝素、亚精胺和Be2+离子对大鼠肝细胞核ATP酶、β-甘油磷酸酶和RNA酶活性的影响。结果表明，Be2+能抑制ATP酶活性，对β-甘油磷酸酶活性的抑制作用较小。生理浓度的肝素和亚精胺也能降低上述两种酶的活性以及细胞核的RNA酶活性。文中提供了肝素和亚精胺对内切核酸酶具有抑制作用的证据。
