SIC-BIO, Bioelectronics and Nanobioengineering Group, Department of Electronics, University of Barcelona, Marti i Franques, 1, 08028, Barcelona, Spain.
Sensors (Basel). 2012;12(1):686-703. doi: 10.3390/s120100686. Epub 2012 Jan 10.
The time required to image large samples is an important limiting factor in SPM-based systems. In multiprobe setups, especially when working with biological samples, this drawback can make impossible to conduct certain experiments. In this work, we present a feedfordward controller based on bang-bang and adaptive controls. The controls are based in the difference between the maximum speeds that can be used for imaging depending on the flatness of the sample zone. Topographic images of Escherichia coli bacteria samples were acquired using the implemented controllers. Results show that to go faster in the flat zones, rather than using a constant scanning speed for the whole image, speeds up the imaging process of large samples by up to a 4× factor.
在基于 SPM 的系统中，对大样本进行成像所需的时间是一个重要的限制因素。在多探头设置中，特别是在处理生物样本时，这一缺点可能使得某些实验无法进行。在这项工作中，我们提出了一种基于 bang-bang 和自适应控制的前馈控制器。这些控制是基于根据样品区域的平整度可以使用的最大速度之间的差异来实现的。使用实现的控制器获取了大肠杆菌细菌样本的地形图像。结果表明，为了在平坦区域更快地进行成像，而不是对整个图像使用恒定的扫描速度，可以将大样本的成像过程提速高达 4 倍。
