Department of Italian Navy Health, Taranto, Italy.
G Ital Dermatol Venereol. 2012 Feb;147(1):83-90.
A negative impact on vitiligo patients in terms of quality of life (QoL) has been suggested. The aim of this report was to study the QoL in a sample of Italian vitiligo patients by using the Dermatology Life Quality Index (DLQI) questionnaire.
A sample of forty seven vitiligo subjects, identified among 34,740 potential conscripts resident in southern Italy underwent the Italian version of the DLQI questionnaire.
The median total DLQI score was 1 (IQR: 2; mean: 1.82). In univariate analysis, DLQI total score was significantly influenced by the clinical course of vitiligo, disease extension over the body, and location on face and/or hands. Multivariate analysis using logistic stepwise regression showed that only the localization on the hands and on the face influenced significantly the mean DLQI.
Our study conducted on a random sample of individuals affected by vitiligo selected from the general young male population in Italy, does not document a large impact of vitiligo on QoL. However, variations exist and the location of lesions on the face and/or hands may impact on QoL. Population-based studies are not affected by selection biases connected with seeking medical care and should be more widely performed.
有人认为白癜风患者的生活质量（QoL）受到负面影响。本报告的目的是通过使用皮肤病生活质量指数（DLQI）问卷研究意大利白癜风患者的生活质量。
在意大利南部的 34740 名应征者中，我们选取了 47 名白癜风患者作为样本，让他们填写意大利版 DLQI 问卷。
中位数总 DLQI 得分为 1（IQR：2；均值：1.82）。在单因素分析中，DLQI 总分受白癜风病程、疾病在全身的扩展程度、面部和/或手部的位置显著影响。使用逻辑逐步回归的多因素分析表明，只有手部和面部的定位显著影响平均 DLQI。
我们在意大利普通年轻男性人群中随机抽取的白癜风患者样本中进行的研究并未发现白癜风对 QoL 有较大影响。然而，存在个体差异，面部和/或手部的病变位置可能会影响 QoL。基于人群的研究不受与寻求医疗相关的选择偏差的影响，应更广泛地开展此类研究。
