From the Department of Family and Community Medicine (Al-Shammari), College of Medicine; from the College of Medicine (Alotaibi, Assiri, Altokhais, Alotaibi), King Saud University, Riyadh; and from the Department of Dermatology (Alkhowailed), College of Medicine, Qassim University, Buraidah, Qassim, Kingdom of Saudi Arabia.
Saudi Med J. 2021 Jun;42(6):682-687. doi: 10.15537/smj.2021.42.6.20200833.
To assess the quality of life (QoL) in patients with vitiligo in central Saudi Arabia using the dermatology life quality index (DLQI).
A cross-sectional study spanning over 6 months was conducted on 253 adult patients with vitiligo at the outpatient dermatology clinics of the National Center of Vitiligo (Light Clinics) and King Khalid University Hospital, Riyadh, Saudi Arabia. The patients were asked to complete a self-administered questionnaire using an Arabic version of the DLQI to measure the impact of vitiligo on their QoL. The association between the demographic and diseases characteristic to the median DLQI scores was investigated using binary logistic regression.
The median DLQI score was 4, the range 25, min 0 - max 25 and percentiles 2-8. The unadjusted odds ratio (95%CI) showed the median DLQI score was significantly higher in married subjects 2.29 (1.33-3.94) (<0.01), non-segmental vitiligo 2.10 (1.16-3.79) (<0.01), and the progressive vitiligo 1.87 (1.09-3.18) (<0.02) than their counterparts. However, after adjustment only married status predicted the high DLQI score 2.08 (1.11-3.61) (<0.01).
The QoL in vitiligo patients in Saudi Arabia is adverse than those with lighter skin, in other countries. Therefore, in Saudi Arabia, better management modalities to improve patients' QoL and prevent subsequent mental distress are needed.
使用皮肤病生活质量指数（DLQI）评估沙特阿拉伯中部白癜风患者的生活质量（QoL）。
在沙特阿拉伯利雅得的国家白癜风中心（Light Clinics）和 King Khalid 大学医院的皮肤科门诊进行了为期 6 个月的横断面研究，共纳入 253 名成年白癜风患者。患者被要求使用阿拉伯语版 DLQI 填写自我管理问卷，以评估白癜风对其生活质量的影响。使用二元逻辑回归分析调查人口统计学和疾病特征与中位数 DLQI 评分之间的关系。
中位数 DLQI 评分为 4 分，范围为 25 分，最小值为 0 分，最大值为 25 分，百分位数为 2-8。未调整的优势比（95%CI）显示，与未婚相比，已婚受试者的中位数 DLQI 评分显著更高，比值比为 2.29（1.33-3.94）（<0.01），非节段性白癜风为 2.10（1.16-3.79）（<0.01），进展性白癜风为 1.87（1.09-3.18）（<0.02）。然而，调整后只有已婚状态预测了较高的 DLQI 评分，比值比为 2.08（1.11-3.61）（<0.01）。
与其他国家相比，沙特阿拉伯白癜风患者的生活质量较差。因此，在沙特阿拉伯，需要更好的管理方式来改善患者的生活质量，预防后续的精神困扰。
