CoroVital Institute for Sports Medicine, Wuppertal, Germany.
Arq Bras Cardiol. 2012 Mar;98(3):234-42. doi: 10.1590/s0066-782x2012005000017. Epub 2012 Feb 29.
Transthoracic echocardiography (TTE) is routinely used to calculate aortic valve area (AVA) by continuity equation (CE). However, accurate measurement of the left ventricular outflow tract (LVOT) can be difficult and flow acceleration in the LVOT may lead to miscalculation of the AVA.
The aim of our study was to compare AVA measurements by standard TTE, cardiac magnetic resonance imaging (MRI) and a hybrid approach combining both techniques.
AVA was calculated in 38 patients (age 73±9 years) with standard TTE, cine-MRI planimetry and a hybrid approach: Hybrid Method 1: TTE-derived LVOT measurement in the CE numerator was replaced by the MRI assessment of the LVOT and AVA was calculated: (LVOT(MRI)/*LVOT-VTI(TTE))/transaortic-VTI(TTE). Method 2: We replaced the SV in the numerator by the MRI-derived SV and calculated AVA = SV(MRI)/ transaortic-VTI(TTE).
Mean AVA derived by TTE was 0.86 cm(2)±0.23 cm(2) and 0.83 cm(2)±0.3 cm(2) by MRI- planimetry, respectively. The mean absolute difference in AVA was 0.03 cm(2) for TTE vs. MRI planimetry. AVA calculated with method 1 and method 2 was 1.23 cm(2)±0.4 cm(2) and 0.92 cm(2)±0.32 cm(2), respectively. The mean absolute difference between TTE and method 1 and method 2 was 0.37 cm(2) and 0.06 cm(2), respectively (p<0.001).
MRI-planimetry of AVA and hybrid method 2 are accurate and showed a good agreement with standard TTE measurements. Therefore, hybrid method 1 is a reasonable alternative if poor acoustic windows or LVOT flow accelerations limit the accuracy of TTE, particularly in patients at high risk for an invasive hemodynamic study.
经胸超声心动图(TTE)通常用于通过连续方程(CE)计算主动脉瓣口面积(AVA)。然而,左心室流出道(LVOT)的准确测量可能很困难,并且 LVOT 中的流速加速可能导致 AVA 的计算错误。
我们的研究目的是比较标准 TTE、心脏磁共振成像(MRI)和结合这两种技术的混合方法测量的 AVA。
对 38 例患者(年龄 73±9 岁)进行了 AVA 测量,使用标准 TTE、电影 MRI 平面测量和混合方法:混合方法 1:用 MRI 评估 LVOT 代替 TTE 中 CE 分子中的 LVOT 测量,计算 AVA:(LVOT(MRI)/*LVOT-VTI(TTE))/transaortic-VTI(TTE)。方法 2:我们用 MRI 衍生的 SV 代替分子中的 SV,计算 AVA = SV(MRI)/transaortic-VTI(TTE)。
TTE 得出的平均 AVA 为 0.86 cm(2)±0.23 cm(2),MRI-平面测量法得出的平均 AVA 为 0.83 cm(2)±0.3 cm(2)。TTE 与 MRI 平面测量法之间的平均绝对差异为 0.03 cm(2)。方法 1 和方法 2 计算的 AVA 分别为 1.23 cm(2)±0.4 cm(2)和 0.92 cm(2)±0.32 cm(2)。TTE 与方法 1 和方法 2 的平均绝对差异分别为 0.37 cm(2)和 0.06 cm(2)(p<0.001)。
AVA 的 MRI 平面测量和混合方法 2 是准确的,与标准 TTE 测量具有良好的一致性。因此,如果声学窗差或 LVOT 流速加速限制了 TTE 的准确性,特别是在高风险的有创血流动力学研究患者中,混合方法 1 是一种合理的替代方法。