Shiau Tiffany, Armogan Narendra, Yan David B, Thomson Hugh G, Levin Alex V
Jefferson Medical College of Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
J AAPOS. 2012 Feb;16(1):61-4. doi: 10.1016/j.jaapos.2011.09.014.
To evaluate the role of episcleral venous pressure (EVP) in the pathogenesis of glaucoma associated with Sturge-Weber syndrome (SWS).
EVPs were determined prospectively using an episcleral venomanometer in 22 eyes of 11 patients aged 8-18 years with SWS with or without glaucoma. Pressure measurements in the glaucomatous eyes of patients with SWS were compared to those of patients with facial port wine marks but no glaucoma and to the contralateral uninvolved eye in both groups.
EVP in eyes with glaucoma (mean, 20.9 mm Hg) was significantly higher (P < 0.01) than EVP in contralateral uninvolved eyes (mean, 9.6 mm Hg). In patients with unilateral port wine mark and no glaucoma, EVP was normal for ipsilateral and contralateral eyes (mean, 8.6 mm Hg and 9.6 mm Hg, respectively).
Our data support the hypothesis that elevated EVP plays an important role in eyes with SWS glaucoma.
评估巩膜静脉压（EVP）在与斯-韦综合征（SWS）相关的青光眼发病机制中的作用。
前瞻性地使用巩膜静脉压力计测定11例年龄在8至18岁、患有或未患有青光眼的SWS患者的22只眼睛的EVP。将SWS患者青光眼患眼的压力测量值与有面部葡萄酒色斑但无青光眼的患者以及两组对侧未受累眼的压力测量值进行比较。
青光眼患眼的EVP（平均20.9 mmHg）显著高于对侧未受累眼（平均9.6 mmHg）（P < 0.01）。在患有单侧葡萄酒色斑且无青光眼的患者中，同侧和对侧眼睛的EVP均正常（分别为平均8.6 mmHg和9.6 mmHg）。
我们的数据支持以下假设，即EVP升高在SWS青光眼患眼中起重要作用。
