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巴西塞阿拉地区阿萨希毛孢子菌的分离及抗真菌药敏试验

Isolation and antifungal susceptibility testing of Trichosporon asahii in Ceará, Brazil.

作者信息

Menezes Everardo Albuquerque, Marinho José Arlécio de Sousa, Angelo Maria Rozzelê F, Cunha Maria da Conceição dos Santos Oliveira, Cunha Francisco Afrânio, Vasconcelos Júnior Antônio Alexandre de

机构信息

Laboratory of Microbiology of Yeasts, Department of Clinical and Toxicological Analysis, College of Pharmacy, Federal University of Ceará, Brasil.

出版信息

Rev Inst Med Trop Sao Paulo. 2012 Jan-Feb;54(1):1-3. doi: 10.1590/s0036-46652012000100001.

DOI:10.1590/s0036-46652012000100001
PMID:22370746
Abstract

Trichosporon spp. are yeasts capable of causing invasive disease, which mainly affect immunocompromised patients. A clinical strain of T. asahii was isolated from the blood cultures of patients admitted to the General Hospital of Fortaleza. Susceptibility tests were conducted by disk diffusion and broth microdilution. The isolated strain of T. asahii was resistant to fluconazole. The patient used amphotericin B and caspofungin in order to facilitate the microbiological cure. It was the first isolation and identification of T. asahii in blood culture in Ceará, Brazil.

摘要

毛孢子菌属是能够引起侵袭性疾病的酵母菌,主要影响免疫功能低下的患者。一株阿萨希毛孢子菌临床菌株从福塔莱萨综合医院收治患者的血培养物中分离得到。采用纸片扩散法和肉汤微量稀释法进行药敏试验。分离出的阿萨希毛孢子菌菌株对氟康唑耐药。该患者使用两性霉素B和卡泊芬净以促进微生物学治愈。这是巴西塞阿拉州首次从血培养中分离和鉴定出阿萨希毛孢子菌。

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