Graduate School of Life Sciences, Tohoku University, 2-1-1 Katahira, Aoba, Sendai, Miyagi 980-8577, Japan.
Plant Cell Rep. 2012 Jul;31(7):1227-32. doi: 10.1007/s00299-012-1243-y. Epub 2012 Feb 28.
We previously proposed the defensive role of a signal pathway triggered by the polyamine spermine (Spm) in the reaction against avirulent viral pathogens in Nicotiana tabacum and Arabidopsis thaliana. In this study, we showed that thermospermine (T-Spm), an isomer of Spm, is also active in inducing the expression of the genes involved in the Spm-signal pathway at a similar dose as Spm. Furthermore, we found that T-Spm enhances the expression of a subset of pathogenesis-related genes whose expression is induced during cucumber mosaic virus (CMV)-triggered hypersensitive response. In consistent with the above observation, we further showed that exogenous T-Spm can repress CMV multiplication with same efficiency as Spm.
Polyamine thermospermine, an isomer of spermine, is able to induce a subset of hypersensitive response-related defense genes and can suppress cucumber mosaic virus multiplication in Arabidopsis thaliana.
我们之前提出了多胺亚精胺（Spm）触发的信号通路的防御作用，该信号通路在烟草和拟南芥中针对无毒病毒病原体的反应中起作用。在这项研究中，我们表明，热亚精胺（T-Spm）是 Spm 的一种异构体，在类似 Spm 的剂量下也能激活参与 Spm 信号通路的基因的表达。此外，我们发现 T-Spm 增强了一组与病程相关基因的表达，这些基因在黄瓜花叶病毒（CMV）触发的过敏反应中被诱导表达。与上述观察结果一致，我们还表明，外源性 T-Spm 可以像 Spm 一样有效地抑制 CMV 的增殖。
多胺热亚精胺是亚精胺的一种异构体，能够诱导一组与过敏反应相关的防御基因，并能抑制拟南芥中黄瓜花叶病毒的增殖。
