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以色列、约旦河西岸和加沙地带的麻疹:持续的发病率及新的根除策略的理由。

Measles in Israel, the West Bank, and Gaza: continuing incidence and the case for a new eradication strategy.

作者信息

Tulchinsky T H, Abed Y, Ginsberg G, Shaheen S, Friedman J B, Schoenbaum M L, Slater P E

机构信息

Department of Epidemiology, Ministry of Health, Jerusalem, Israel.

出版信息

Rev Infect Dis. 1990 Sep-Oct;12(5):951-8. doi: 10.1093/clinids/12.5.951.

Abstract

Measles continues to occur in epidemic waves in Israel, Gaza, and the West Bank, causing morbidity and mortality. In Israel, immunization of infants against measles began in 1967, and 90% had been immunized by the mid-1980s. In Gaza and the West Bank, where immunization of infants against measles began in 1973 and 1976, respectively, the immunization rate reached 75% in the late 1970s and increased to greater than 90% in the 1980s. Measles epidemics, which previously had occurred in 5- to 7-year cycles, occurred every 2-4 years in the 1980s and affected individuals who were older than those affected in previous years. Israel's commitment to eradicating measles by 1992 will require a substantially expanded immunization program in comparison with the traditional program that requires immunization of infants alone. The benefits of several alternative immunization strategies considerably exceed their costs. A new, two-dose immunization will be needed as a minimal strategy, and a campaign for administering booster doses to school-aged children may be required as well to achieve control and eradication of measles. Measles is a serious but preventable public health problem; appropriate strategies must be devised by national and international public health officials to control the disease in developing and developed countries.

摘要

在以色列、加沙和西岸,麻疹疫情仍呈波浪式爆发,导致发病和死亡。在以色列,婴儿麻疹免疫接种始于1967年,到20世纪80年代中期,90%的婴儿已接种疫苗。在加沙和西岸,婴儿麻疹免疫接种分别始于1973年和1976年,20世纪70年代末免疫接种率达到75%,80年代升至90%以上。麻疹疫情以前每5至7年爆发一次,20世纪80年代每2至4年爆发一次,且受影响人群的年龄比以往更大。与仅要求婴儿接种疫苗的传统计划相比,以色列要在1992年前根除麻疹,就需要大幅扩大免疫接种计划。几种替代免疫策略的益处大大超过成本。作为最低限度的策略,需要一种新的两剂免疫接种方法,可能还需要开展一项为学龄儿童接种加强剂的运动,以实现对麻疹的控制和根除。麻疹是一个严重但可预防的公共卫生问题;国家和国际公共卫生官员必须制定适当策略,在发展中国家和发达国家控制该疾病。

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