Tulchinsky T H, Ginsberg G M, Abed Y, Angeles M T, Akukwe C, Bonn J
Preventive Health Services, Ministry of Health, Jerusalem, Israel.
Bull World Health Organ. 1993;71(1):93-103.
Despite major reductions in the incidence of measles and its complications, measles control with a single dose of the currently used. Schwarz strain vaccine has failed to eradicate the disease in the developed countries. In developing countries an enormous toll of measles deaths and disability continues, despite considerable efforts and increasing immunization coverage. Empirical evidence from a number of countries suggests that a two-dose measles vaccination programme, by improving individual protection and heard immunity can make a major contribution to measles control and elimination of local circulation of the disease. Cost-benefit analysis also supports the two-dose schedule in terms of savings in health costs, and total costs to society. A two-dose measles vaccination programme is therefore an essential component of preventive health care in developing, as well as developed countries for the 1990s.
尽管麻疹及其并发症的发病率已大幅降低，但仅使用一剂目前常用的施瓦茨株疫苗进行麻疹防控，在发达国家未能根除该疾病。在发展中国家，尽管付出了巨大努力且免疫接种覆盖率不断提高，但麻疹导致的死亡和残疾人数仍然众多。一些国家的经验证据表明，两剂次麻疹疫苗接种计划通过提高个体防护和群体免疫力，可为麻疹防控及消除该疾病的本地传播做出重大贡献。成本效益分析也从节省医疗成本和社会总成本的角度支持两剂次接种计划。因此，两剂次麻疹疫苗接种计划是20世纪90年代发展中国家和发达国家预防性医疗保健的重要组成部分。
