Huu Sau Nguyen, Van Cap Lam, Van Thuong Nguyen, Manh Tan Nguyen, Minh Phuong Pham Thi, Hong Son Nguyen, Huu Nghi Dinh, Cam Van Tran, Cao Kiem Pham, Hau Khang Tran, Gandolfi Marco, Satolli Francesca, Feliciani Claudio, Tirant Michael, Vojvodic Aleksandra, Lotti Torello
National hospital of Dermatology and Venereology, Hanoi, Vietnam.
Hanoi Dermatology Hospital, Hanoi, Vietnam.
Open Access Maced J Med Sci. 2019 Jan 29;7(2):287-290. doi: 10.3889/oamjms.2019.096. eCollection 2019 Jan 30.
This study aims to evaluate the effectiveness of Alex Trivantage laser wavelength 755 nm (ATL) in the treatment of freckles at Hanoi Hospital of Dermatology and Venereology, Vietnam.
A group of 30 patients with freckles were treated by ATL (Alex Trivantage-Candela Co America) with spots size 3 mm, wavelength 755 mm, and energy 5-6 j/cm. All the patients were treated 2 times with 4-weeks interval. The results were evaluated at 4, 8, and 12 weeks after treatment. The colour of the lesions was evaluated by using Von-Luchan's chromatic scale and Visia® complex analysis system. Brown spot index (BSI) was calculated by the VISA complexion analysis system devices. The data was analysed by SPSS 16.0.
After 2 times of treatment, the lesion colour of all of the patients had been improved. The good and very good levels of improvement were noted in 63.3% of patients; there was 26.7% of them had partial improvement. Brown spots index was significantly improved (39.13 ± 20.66 before and 54.23 ± 16.78 after treatment; p < 0.001). Hyperpigmentation was noted in 6.7% of patients.
freckles have been improved by treatment with Alex trivantage laser wavelength 755 nm with safety.
本研究旨在评估波长755nm的Alex Trivantage激光（ATL）在越南河内皮肤病与性病医院治疗雀斑的有效性。
一组30例雀斑患者接受ATL（美国科医人公司的Alex Trivantage）治疗，光斑大小3mm，波长755nm，能量5 - 6J/cm²。所有患者均接受2次治疗，间隔4周。在治疗后4周、8周和12周评估结果。采用冯·卢尚氏色标和Visia®综合分析系统评估皮损颜色。通过VISA肤色分析系统设备计算褐斑指数（BSI）。数据采用SPSS 16.0进行分析。
经过2次治疗后，所有患者的皮损颜色均有改善。63.3%的患者改善程度为良好及非常好；26.7%的患者有部分改善。褐斑指数显著改善（治疗前为39.13±20.66，治疗后为54.23±16.78；p<0.001）。6.7%的患者出现色素沉着。
采用波长755nm的Alex trivantage激光治疗雀斑安全有效，皮损得到改善。
