Centre de Recherche en Amélioration Végétale, Département de Biologie, Université de Sherbrooke, Sherbrooke, Quebec J1K2R1, Canada.
Plant Cell. 2012 Feb;24(2):762-77. doi: 10.1105/tpc.111.095190. Epub 2012 Feb 28.
Auxin is a pivotal plant hormone that regulates many aspects of plant growth and development. Auxin signaling is also known to promote plant disease caused by plant pathogens. However, the mechanism by which this hormone confers susceptibility to pathogens is not well understood. Here, we present evidence that fungal and bacterial plant pathogens hijack the host auxin metabolism in Arabidopsis thaliana, leading to the accumulation of a conjugated form of the hormone, indole-3-acetic acid (IAA)-Asp, to promote disease development. We also show that IAA-Asp increases pathogen progression in the plant by regulating the transcription of virulence genes. These data highlight a novel mechanism to promote plant susceptibility to pathogens through auxin conjugation.
生长素是一种关键的植物激素，调节植物生长和发育的许多方面。生长素信号也被认为可以促进植物病原体引起的植物病害。然而，这种激素赋予病原体易感性的机制尚不清楚。在这里，我们提供的证据表明，真菌和细菌植物病原体在拟南芥中劫持了宿主生长素代谢，导致激素吲哚-3-乙酸（IAA）-天冬氨酸的共轭形式积累，从而促进疾病的发展。我们还表明，IAA-Asp 通过调节毒力基因的转录来增加植物中的病原体进展。这些数据突出了通过生长素共轭促进植物对病原体易感性的新机制。
