Centre for Public Health Research, Kenya Medical Research Institute, Nairobi, Kenya.
Diabetes Care. 2012 Apr;35(4):887-93. doi: 10.2337/dc11-0537. Epub 2012 Feb 28.
Developing countries are undergoing an epidemiologic transition accompanied by increasing burden of cardiovascular disease (CVD) linked to urbanization and lifestyle modifications. Metabolic syndrome is a cluster of CVD risk factors whose extent in Kenya remains unknown. The aim of this study was to determine the prevalence of metabolic syndrome and factors associated with its occurrence among an urban population in Kenya.
This was a household cross-sectional survey comprising 539 adults (aged ≥18 years) living in Nairobi, drawn from 30 clusters across five socioeconomic classes. Measurements included waist circumference, HDL cholesterol, triacylglycerides (TAGs), fasting glucose, and blood pressure.
The prevalence of metabolic syndrome was 34.6% and was higher in women than in men (40.2 vs. 29%; P < 0.001). The most frequently observed features were raised blood pressure, a higher waist circumference, and low HDL cholesterol (men: 96.2, 80.8, and 80%; women: 89.8, 97.2, and 96.3%, respectively), whereas raised fasting glucose and TAGs were observed less frequently (men: 26.9 and 63.3%; women: 26.9 and 30.6%, respectively). The main factors associated with the presence of metabolic syndrome were increasing age, socioeconomic status, and education.
Metabolic syndrome is prevalent in this urban population, especially among women, but the incidence of individual factors suggests that poor glycemic control is not the major contributor. Longitudinal studies are required to establish true causes of metabolic syndrome in Kenya. The Kenyan government needs to create awareness, develop prevention strategies, and strengthen the health care system to accommodate screening and management of CVDs.
发展中国家正经历着与城市化和生活方式改变相关的心血管疾病(CVD)负担增加的流行病学转变。代谢综合征是一组 CVD 风险因素,其在肯尼亚的严重程度尚不清楚。本研究旨在确定代谢综合征在肯尼亚城市人口中的流行程度及其相关因素。
这是一项家庭横断面调查,包括来自内罗毕 30 个集群的 539 名(年龄≥18 岁)成年人,来自五个社会经济阶层。测量包括腰围、高密度脂蛋白胆固醇(HDL 胆固醇)、三酰甘油(TAGs)、空腹血糖和血压。
代谢综合征的患病率为 34.6%,女性高于男性(40.2%比 29%;P<0.001)。最常见的表现是血压升高、腰围增大和 HDL 胆固醇降低(男性:96.2%、80.8%和 80%;女性:89.8%、97.2%和 96.3%),而空腹血糖和 TAGs 升高则不太常见(男性:26.9%和 63.3%;女性:26.9%和 30.6%)。与代谢综合征存在相关的主要因素是年龄增长、社会经济地位和教育程度。
代谢综合征在该城市人群中很普遍,尤其是在女性中,但个别因素的发生率表明,血糖控制不佳不是主要原因。需要进行纵向研究以确定代谢综合征在肯尼亚的真正原因。肯尼亚政府需要提高认识、制定预防策略,并加强卫生保健系统,以适应 CVD 的筛查和管理。