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中国畲族人群中与高血压前期和高血压相关的患病率及危险因素。

Prevalence and risk factors associated with prehypertension and hypertension in the Chinese She population.

机构信息

Department of Endocrinology, Ningde Municipal Hospital, Ningde, PR China.

出版信息

Kidney Blood Press Res. 2012;35(5):305-13. doi: 10.1159/000336085. Epub 2012 Mar 1.

DOI:10.1159/000336085
PMID:22377586
Abstract

BACKGROUND

Little is known about the prevalence and cardiovascular risk factors for prehypertension and hypertension in the She ethnic minority population of Fujian province in China.

METHODS AND RESULTS

Between April 2009 and September 2009, 5,523 participants of She nationality aged between 20 and 80 years participated in this survey and 5,357 were eventually enrolled in analyses. The survey was carried out to assess blood pressure and cardiovascular risk factors. The prevalence of prehypertension and hypertension was 35.87 and 38.42%, respectively, in all participants. Only 26.63% of the subjects with hypertension were aware of their diagnosis. Multivariate logistic regression showed that age, gender, overweight/obesity, dyslipidemia and alcohol use were risk factors for prehypertension, and age, overweight/obesity, dyslipidemia, alcohol use, family history of hypertension and hyperuricemia were risk factors for hypertension. The clustering of 2 and ≥ 3 risk factors was in higher proportion for subjects with hypertension and prehypertension when compared with those with prehypertension and normotension, respectively. After adjusting for other confounding factors, multivariable logistic regression showed that the greater the number of clustering cardiovascular risk factors, the greater the odds ratios for prehypertension and hypertension are.

CONCLUSION

Hypertension and prehypertension were common in the She population of Fujian province. Cardiovascular risk factors cluster during prehypertension and awareness of hypertension was minimal. Early lifestyle modifications could be advocated to prevent the transition from prehypertension to hypertension and cardiovascular disease.

摘要

背景

在中国福建省的畲族人群中,关于高血压前期和高血压的患病率及其心血管危险因素知之甚少。

方法和结果

2009 年 4 月至 2009 年 9 月期间,共有 5523 名年龄在 20 至 80 岁之间的畲族参与者参加了此项调查,最终有 5357 人纳入分析。该调查旨在评估血压和心血管危险因素。所有参与者中高血压前期和高血压的患病率分别为 35.87%和 38.42%。仅有 26.63%的高血压患者知晓自己的诊断。多变量 logistic 回归分析显示,年龄、性别、超重/肥胖、血脂异常和饮酒是高血压前期的危险因素,而年龄、超重/肥胖、血脂异常、饮酒、高血压家族史和高尿酸血症是高血压的危险因素。与高血压前期和血压正常者相比,高血压和高血压前期患者的 2 种及以上危险因素聚集的比例更高。在校正其他混杂因素后,多变量 logistic 回归分析显示,心血管危险因素聚集的数量越多,高血压前期和高血压的比值比越大。

结论

高血压前期和高血压在福建省的畲族人群中较为常见。高血压前期会出现心血管危险因素聚集,且高血压的知晓率极低。可以提倡早期进行生活方式的改变,以预防从高血压前期向高血压和心血管疾病的转变。

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