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中国 33 个社区城市成年人的高血压前期流行病学及其相关危险因素——CHPSNE 研究。

Epidemiology of prehypertension and associated risk factors in urban adults from 33 communities in China--the CHPSNE study.

机构信息

Division of Neurology, Fourth Affiliated Hospital of China Medical University, Shenyang, PR China.

出版信息

Circ J. 2012;76(4):900-6. doi: 10.1253/circj.cj-11-1118. Epub 2012 Feb 1.

DOI:10.1253/circj.cj-11-1118
PMID:22293448
Abstract

BACKGROUND

The Seventh Report of The Joint National Committee has recently introduced the prehypertension category of blood pressure (BP) status that needs monitoring and intervention. Little is known about the epidemiology of prehypertension in urban China, so this study aimed at estimating the prevalence of prehypertension and identifying risk factors in urban Chinese adults.

METHODS AND RESULTS

Using a multistage cluster and random sampling method, a representative sample of 25,196 urban adults aged 18-74 years in northeast of China was selected from 2009 to 2010. The survey of BP and associated risk factors was carried out in 33 communities. Multiple logistic regression methods were used to identify risk factors for prehypertension. Overall, 40.5% of urban Chinese adults had prehypertension, with a prevalence of 47.7% and 33.6% in men and women, respectively. Multivariate logistic regression analysis revealed the risk factors of being overweight (adjusted odds ratio [aOR]=1.38, 95% confidence interval [CI]: 1.26-1.52), obesity (aOR=3.94, 95%CI: 2.99-5.20), central obesity (aOR=2.13, 95%CI: 1.96-2.32). Being female, and having a higher education level, higher family income and diet control were protective factors.

CONCLUSIONS

Prehypertension is common among urban residents in China, and is associated with many risk factors. Comprehensive lifestyle modifications need to be taken to decrease the incidence of prehypertension and to prevent prehypertension progressing to hypertension and cardiovascular disease.

摘要

背景

最近,美国联合委员会第七次报告引入了血压(BP)状态的高血压前期类别,需要对其进行监测和干预。中国城市高血压前期的流行病学情况尚不清楚,因此本研究旨在评估中国城市成年人高血压前期的患病率,并确定其危险因素。

方法和结果

本研究采用多阶段聚类和随机抽样方法,于 2009 年至 2010 年从中国东北地区选取了 25196 名 18-74 岁的城市成年人作为代表性样本。在 33 个社区进行了血压及相关危险因素的调查。采用多因素逻辑回归方法确定高血压前期的危险因素。结果显示,40.5%的中国城市成年人患有高血压前期,其中男性和女性的患病率分别为 47.7%和 33.6%。多因素逻辑回归分析显示,超重(调整后比值比[aOR]=1.38,95%置信区间[CI]:1.26-1.52)、肥胖(aOR=3.94,95%CI:2.99-5.20)、中心性肥胖(aOR=2.13,95%CI:1.96-2.32)是高血压前期的危险因素。女性、受教育程度较高、家庭收入较高和饮食控制是高血压前期的保护因素。

结论

高血压前期在中国城市居民中较为常见,与多种危险因素相关。需要采取综合的生活方式改变来降低高血压前期的发病率,并预防高血压前期进展为高血压和心血管疾病。

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