超声检查发现的猫胆囊内胆汁淤积可预测其肝酶和总胆红素升高。
Gallbladder sludge on ultrasound is predictive of increased liver enzymes and total bilirubin in cats.
作者信息
Harran Nathaniel, d'Anjou Marc-André, Dunn Marilyn, Beauchamp Guy
机构信息
The Companion Animal Research Group, Département de Sciences Cliniques, Université de Montréal, Saint-Hyacinthe, Québec.
出版信息
Can Vet J. 2011 Sep;52(9):999-1003.
The purposes of this retrospective study were to assess the prevalence of gallbladder sludge (GBS) in a population of cats presented for abdominal ultrasound in a teaching hospital and to determine its association with increased serum alanine aminotransferase (ALT), alkaline phosphatase (ALP), and total bilirubin (TB). Gallbladder sludge was detected in 152 (14%) of the cats undergoing abdominal ultrasound between 2004 and 2008. This population was compared to a control group of 32 cats without GBS. Alanine aminotransferase, ALP, and TB mean values were significantly higher in cats with GBS than in controls (P ≤ 0.0005) and odds for increased values in cats with GBS were 4.2 [95% confidence interval (CI): 1.6 to 11.0], 9.5 (95% CI: 2.2 to 41.7), and 4.1 (95% CI: 1.5 to 11.5), respectively (P ≤ 0.007). In conclusion, GBS is an uncommon ultrasonographic finding in cats that is predictive of increased liver enzymes and TB. More studies are needed to establish potential links between GBS and hepatobiliary disease in cats.
这项回顾性研究的目的是评估一家教学医院中接受腹部超声检查的猫群中胆囊泥沙样物（GBS）的患病率，并确定其与血清丙氨酸氨基转移酶（ALT）、碱性磷酸酶（ALP）和总胆红素（TB）升高之间的关联。在2004年至2008年期间接受腹部超声检查的猫中，有152只（14%）检测到胆囊泥沙样物。将该群体与32只无GBS的猫组成的对照组进行比较。GBS猫的ALT、ALP和TB平均值显著高于对照组（P≤0.0005），GBS猫各项指标升高的比值分别为4.2[95%置信区间（CI）：1.6至11.0]、9.5（95%CI：2.2至41.7）和4.1（95%CI：1.5至11.5）（P≤0.007）。总之，GBS在猫中是一种不常见的超声检查发现，可预测肝酶和TB升高。需要更多研究来确定GBS与猫肝胆疾病之间的潜在联系。
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