Chen Eric, Itkin Maxim
Division of Interventional Radiology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.
Semin Intervent Radiol. 2011 Mar;28(1):63-74. doi: 10.1055/s-0031-1273941.
Chylous leaks, such as chylothorax and chylopericardium, are uncommon effusions resulting from the leakage of intestinal lymphatic fluid from the thoracic duct (TD) and its tributaries, or intestinal lymphatic ducts. The cause can be either traumatic (thoracic surgery) or nontraumatic (idiopathic, malignancy). Treatment has traditionally consisted of dietary modification (nonfat diet) and/or surgery (TD ligation, pleurodesis). Thoracic duct embolization (TDE) has become a viable treatment alternative due to it high success rate and minimal complications. In this article, the authors describe the etiologies of chylothorax, patient population, outcomes, and long-term follow-up of TDE patients. Relevant lymphatic anatomy and physiology are reviewed, with special attention paid to the formation of the duct by tributaries at the cisterna chyli (CC). The technique of TDE is outlined, including bilateral pedal lymphangiography, TD cannulation, and embolic agents used for the procedure.
乳糜漏,如乳糜胸和乳糜心包,是一种罕见的积液,由胸导管(TD)及其分支或肠淋巴管漏出的肠道淋巴液引起。其病因可以是创伤性的(胸外科手术)或非创伤性的(特发性、恶性肿瘤)。传统的治疗方法包括饮食调整(无脂饮食)和/或手术(TD结扎、胸膜固定术)。由于胸导管栓塞术(TDE)成功率高且并发症少,已成为一种可行的治疗选择。在本文中,作者描述了乳糜胸的病因、患者群体、治疗结果以及TDE患者的长期随访情况。回顾了相关的淋巴解剖学和生理学,特别关注乳糜池(CC)处分支形成导管的情况。概述了TDE技术,包括双侧足背淋巴管造影、TD插管以及该手术使用的栓塞剂。