School of Life Sciences and Biotechnology, Korea University, Seoul, South Korea.
Pest Manag Sci. 2012 Jul;68(7):1062-8. doi: 10.1002/ps.3268. Epub 2012 Mar 2.
In the natural environment, photodegradation is one of the most common degradative processes of pesticides. In order to reduce the photodegradation of pesticides, and so increase their killing activity against target pests, chitosan-coated beeswax solid lipid nanoparticles (CH-BSLNs) were prepared by a combination of hot homogenization and sonication, with deltamethrin as an active ingredient.
Under optimal conditions, the highest encapsulation efficiency (95%) and a high payload of deltamethrin (approximately 12.5%) were achieved. In direct photolysis, in the case of CH-BSLNs after UV irradiation for 24 h, 37.3% of deltamethrin remained, as opposed to only 14.6% of the free-form deltamethrin. In addition, in indirect photolysis, in the case of CH-BSLNs after UV irradiation for 2 h in 2% acetone solution, approximately 74.5% of deltamethrin remained, as opposed to only 37.6% of the free-form deltamethrin.
CH-BSLNs showed good protection for deltamethrin against photodegradation. This novel nanocarrier may be useful in crop protection as an economical strategy to enhance the effect of pesticides in the field and protect the environment as well.
在自然环境中，光降解是农药最常见的降解过程之一。为了减少农药的光降解，提高其对靶标害虫的杀虫活性，本研究采用热匀相法和超声法相结合，以除虫菊酯为活性成分，制备了壳聚糖包裹的蜂蜡固体脂质纳米粒（CH-BSLNs）。
在最优条件下，CH-BSLNs 达到了最高的包封效率（95%）和较高的载药量（约 12.5%）。在直接光解中，CH-BSLNs 在紫外光照射 24 小时后，仍有 37.3%的除虫菊酯残留，而游离态除虫菊酯仅残留 14.6%。此外，在间接光解中，CH-BSLNs 在 2%丙酮溶液中紫外光照射 2 小时后，仍有 74.5%的除虫菊酯残留，而游离态除虫菊酯仅残留 37.6%。
CH-BSLNs 对除虫菊酯的光降解具有良好的保护作用。这种新型纳米载体可作为一种经济有效的策略，用于作物保护，提高田间农药效果，保护环境。
