中国湛江甲型H1N1流感大流行（2009年）的流行病学特征
Epidemiological characteristics of pandemic influenza A (H1N1-2009) in Zhanjiang, China.
作者信息
Fu JinJian, Chen SiDong, Chen JiaLin, Wang Jie, Ling ChenWen
机构信息
Department of Epidemiology, Southern Medical University, Guangzhou, China.
出版信息
Pan Afr Med J. 2011;10:54. Epub 2011 Dec 14.
BACKGROUND
A novel influenza A virus strain (H1N1-2009) spread first in Mexico and the United Stated in late April 2009, leading to the first influenza pandemic of the 21(st) century. The objective of this study was to determine the epidemiological and virological characteristics of the pandemic influenza A (H1N1-2009) in Zhanjiang, China.
METHODS
The case and outbreak reports of influenza-like illness (ILI) were collected from the Chinese information system of disease control and prevention and the influenza surveillance system of Zhanjiang city. Real-time RT-PCR was conducted, and epidemic and virological characteristics of the virus were analyzed using descriptive epidemiological methods and Chi-square trend tests.
RESULTS
A total of 276 reported cases were confirmed from July 16, 2009 to June 30, 2010. The attack rate of outbreak was from 1.1% to 6.0%. The disease peak occurred in December 2009, after which the outbreak subsided gradually. The last case was confirmed in April 2010.
CONCLUSION
The main population struck by the H1N1-2009 virus was young adults, youths and children. The outbreaks most frequently occurred in schools, and most cases were acquired locally.
背景
一种新型甲型流感病毒株（H1N1-2009）于2009年4月下旬首先在墨西哥和美国传播，引发了21世纪的首次流感大流行。本研究的目的是确定中国湛江甲型H1N1-2009大流行性流感的流行病学和病毒学特征。
方法
从中国疾病预防控制信息系统和湛江市流感监测系统收集流感样疾病（ILI）的病例和暴发报告。进行实时逆转录聚合酶链反应（RT-PCR），并采用描述性流行病学方法和卡方趋势检验分析病毒的流行特征和病毒学特征。
结果
2009年7月16日至2010年6月30日共报告确诊病例276例。暴发的罹患率为1.1%至6.0%。疾病高峰出现在2009年12月，此后暴发逐渐平息。最后一例确诊病例在2010年4月。
结论
H1N1-2009病毒感染的主要人群为青壮年及儿童。暴发最常发生在学校，且大多数病例为本地感染。
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