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专门的骨组织干细胞。

Special stem cells for bone.

机构信息

The Mount Sinai Bone Program, Department of Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA.

出版信息

Cell Stem Cell. 2012 Mar 2;10(3):233-4. doi: 10.1016/j.stem.2012.02.012.

DOI:10.1016/j.stem.2012.02.012
PMID:22385649
Abstract

Mesenchymal stem cells (MSCs) are multipotential in vitro, but their endogenous properties are poorly defined. In this issue of Cell Stem Cell, Park et al. (2012) report that an MSC-like, osteolineage-directed Mx1+ population generates new osteoblasts at sites of bone damage, suggesting its potential for skeletal repair and regeneration.

摘要

间充质干细胞(MSCs)在体外具有多能性,但它们的内源性特性尚未完全明确。在本期的《Cell Stem Cell》杂志上,Park 等人(2012)报告称,一种 MSC 样、成骨谱系定向的 Mx1+细胞群体可在骨损伤部位产生新的成骨细胞,这提示其在骨骼修复和再生方面的潜在应用。

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