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经典造血细胞因子的血管生成活性。

Angiogenic activity of classical hematopoietic cytokines.

机构信息

Department of Basic Medical Sciences, Section of Human Anatomy and Histology, University of Bari Medical School, Bari, Italy.

出版信息

Leuk Res. 2012 May;36(5):537-43. doi: 10.1016/j.leukres.2012.02.003. Epub 2012 Mar 2.

DOI:10.1016/j.leukres.2012.02.003
PMID:22386730
Abstract

Hematopoiesis is regulated by several cytokines with pleiotropic activity. Several evidences have clearly demonstrated that these molecules, formerly regarded as specific for the hematopoietic system, also affect certain endothelial cell functions and that hematopoietic factors clearly influence angiogenesis. This review article summarizes the most important literature data concerning this inconvertible relationship.

摘要

造血是由几种具有多效性活性的细胞因子调节的。有几项证据清楚地表明,这些以前被认为是专门针对造血系统的分子,也会影响某些内皮细胞的功能,而造血因子也会明显影响血管生成。本文综述了关于这种不可逆转关系的最重要的文献数据。

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1
Angiogenic activity of classical hematopoietic cytokines.经典造血细胞因子的血管生成活性。
Leuk Res. 2012 May;36(5):537-43. doi: 10.1016/j.leukres.2012.02.003. Epub 2012 Mar 2.
2
In vitro and in vivo activation of endothelial cells by colony-stimulating factors.集落刺激因子对内皮细胞的体外和体内激活作用。
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Stromal cell-derived factor and granulocyte-monocyte colony-stimulating factor form a combined neovasculogenic therapy for ischemic cardiomyopathy.基质细胞衍生因子和粒细胞-单核细胞集落刺激因子构成了一种用于缺血性心肌病的联合新生血管生成疗法。
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Influence of combinations of cytokines on proliferation of isolated single cell-sorted human bone marrow hematopoietic progenitor cells in the absence and presence of serum.细胞因子组合在无血清和有血清情况下对分离的单细胞分选的人骨髓造血祖细胞增殖的影响。
Exp Hematol. 1992 Feb;20(2):276-9.
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Oxygen tension alters the effects of cytokines on the megakaryocyte, erythrocyte, and granulocyte lineages.氧分压会改变细胞因子对巨核细胞、红细胞和粒细胞谱系的影响。
Exp Hematol. 1998 Aug;26(9):835-43.
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Hematopoietic growth factors.造血生长因子
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Granulocyte and granulocyte macrophage colony-stimulating factors as therapy in human and veterinary medicine.粒细胞和粒细胞巨噬细胞集落刺激因子在人类和兽医学中的治疗应用。
Vet J. 2007 Jul;174(1):33-41. doi: 10.1016/j.tvjl.2006.08.001. Epub 2006 Oct 9.
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Culture and characterization of hematopoietic progenitor cells from miniature swine.小型猪造血祖细胞的培养与鉴定
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Interactions among colony-stimulating factors, IL-1 beta, IL-6, and kit-ligand in the regulation of primitive murine hematopoietic cells.集落刺激因子、白细胞介素-1β、白细胞介素-6和kit配体在原始小鼠造血细胞调节中的相互作用。
Exp Hematol. 1992 Mar;20(3):339-49.

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Melanoma exosome induction of endothelial cell GM-CSF in pre-metastatic lymph nodes may result in different M1 and M2 macrophage mediated angiogenic processes.黑色素瘤外泌体诱导转移前淋巴结中的内皮细胞产生GM-CSF可能导致不同的M1和M2巨噬细胞介导的血管生成过程。
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