Department of Basic Medical Sciences, Section of Human Anatomy and Histology, University of Bari Medical School, Bari, Italy.
Leuk Res. 2012 May;36(5):537-43. doi: 10.1016/j.leukres.2012.02.003. Epub 2012 Mar 2.
Hematopoiesis is regulated by several cytokines with pleiotropic activity. Several evidences have clearly demonstrated that these molecules, formerly regarded as specific for the hematopoietic system, also affect certain endothelial cell functions and that hematopoietic factors clearly influence angiogenesis. This review article summarizes the most important literature data concerning this inconvertible relationship.
造血是由几种具有多效性活性的细胞因子调节的。有几项证据清楚地表明,这些以前被认为是专门针对造血系统的分子,也会影响某些内皮细胞的功能,而造血因子也会明显影响血管生成。本文综述了关于这种不可逆转关系的最重要的文献数据。