Vedunova S L, Mal'tseva N N
Zh Mikrobiol Epidemiol Immunobiol. 1990 Aug(8):74-8.
The sensitivity and specificity of the enzyme immunoassay (the capture variant), based on the use of the complex of anti-IgM-IgM to purified measles virus, the peroxidase-labeled lysate and nucleocapsid antigens of measles virus, were evaluated. The advantages of the nucleocapsid conjugate were established. The study of 200 serum samples from measles patients revealed that antimeasles IgM antibodies could be detected in 100% of cases, and the assay of 15 serum samples from healthy donors and 5 serum samples from patients with autoimmune diseases did not yield a single false positive result.
基于使用抗IgM-IgM复合物与纯化麻疹病毒、过氧化物酶标记的麻疹病毒裂解物和核衣壳抗原，对酶免疫测定法（捕获变体）的敏感性和特异性进行了评估。确定了核衣壳缀合物的优势。对200份麻疹患者血清样本的研究表明，100%的病例中均可检测到抗麻疹IgM抗体，对15份健康供者血清样本和5份自身免疫性疾病患者血清样本进行检测，未产生一例假阳性结果。
