Allergy and Cancer Center, Otorhinolaryngology Hospital, First Affiliated Hospital of Sun Yat-sen University, No. 58 Zhongshan 2nd Road, Guangzhou, China.
Am J Rhinol Allergy. 2012 Jan-Feb;26(1):e20-2. doi: 10.2500/ajra.2012.26.3738.
Although the prevalence of aspirin-exacerbated respiratory disease (AERD) in western populations is high, AERD is rather rare in China, and few related studies have been published to date.
We performed a prospective cohort investigation on the incidence of AERD in patients with chronic rhinosinusitis (CRS) in southern China. A literature search of the China Academic Journal Network Publishing Database was conducted to obtain an overview of the incidence of AERD in the Chinese population, and previous studies on the incidence of AERD were reviewed.
We found 2 patients with aspirin hypersensitivity among 351 consecutive CRS (309 with nasal polyps [NPs]) patients, suggesting a rate of 0.57% in the CRS population. Forty-five articles about AERD were obtained by Chinese-language literature searches. In total, 346 cases of AERD were reported during the past 30 years.
Given the large population of NPs in China, the prevalence of AERD is very low, and this may be related to the reduced levels of nasal tissue eosinophilia and subsequent low asthma comorbidity.
尽管西方人群中阿司匹林加重的呼吸道疾病（AERD）的患病率较高，但 AERD 在我国却相当罕见，迄今为止，发表的相关研究也很少。
我们对中国南方慢性鼻-鼻窦炎（CRS）患者中 AERD 的发生率进行了前瞻性队列研究。通过中国学术期刊网络出版数据库进行文献检索，以获得中国人群中 AERD 发生率的概述，并对之前关于 AERD 发生率的研究进行了回顾。
我们在 351 例连续 CRS（309 例伴鼻息肉[NP]）患者中发现了 2 例阿司匹林过敏患者，提示 CRS 人群中的发生率为 0.57%。通过中文文献检索获得了 45 篇关于 AERD 的文章。在过去的 30 年中，共报道了 346 例 AERD 病例。
鉴于中国 NP 患者数量庞大，AERD 的患病率非常低，这可能与鼻组织嗜酸性粒细胞减少以及随后哮喘合并症低有关。
