Watanabe K, Kishida K, Hayashi Y, Ozasa H, Masuno H, Haneda N, Nishio T, Mori C
Department of Pediatrics, Shimane Medical University, Japan.
Acta Paediatr Jpn. 1990 Jun;32(3):275-81. doi: 10.1111/j.1442-200x.1990.tb00825.x.
We analyzed the relations between blood pressure in sitting and supine positions, left ventricular mass (LVM) and Doppler aortic, pulmonary and mitral flow velocity measurements in 163 healthy school children. Systolic blood pressure in a supine position correlated significantly with aortic acceleration (ATc) and ejection time (ETc), corrected by the square of R-R interval, pulmonary AT and peak flow velocities. Moreover, the systolic blood pressure in a sitting position correlated with pulmonary AT and LVM. LVM correlated with pulmonary ATc, the ratio of AT to ET and average acceleration, and aortic ETc and peak flow velocity. These data suggest the following: (1) the posture influences the relation between blood pressure and flow velocity, (2) pulmonary hemodynamics are influenced by systemic blood pressure in healthy children and (3) the development of LVM may be dependent not only on blood pressure but also on cardiac work in childhood.
我们分析了163名健康学童的坐位和仰卧位血压、左心室质量(LVM)以及多普勒测量的主动脉、肺动脉和二尖瓣血流速度之间的关系。仰卧位收缩压与经R-R间期平方校正的主动脉加速时间(ATc)和射血时间(ETc)、肺动脉AT及峰值流速显著相关。此外,坐位收缩压与肺动脉AT和LVM相关。LVM与肺动脉ATc、AT与ET的比值以及平均加速度、主动脉ETc和峰值流速相关。这些数据表明:(1)体位影响血压与流速之间的关系;(2)健康儿童的肺血流动力学受全身血压影响;(3)儿童期LVM的发育可能不仅取决于血压,还取决于心脏做功。