Gardin J M, Davidson D M, Rohan M K, Butman S, Knoll M, Garcia R, Dubria S, Gardin S K, Henry W L
Am Heart J. 1987 Jan;113(1):101-9. doi: 10.1016/0002-8703(87)90016-0.
Previous studies have demonstrated a relationship between both age and body surface area (BSA) and M-mode echocardiographic measurements of left ventricular, left atrial, and aortic root dimensions and left ventricular wall thickness. We evaluated the relationships between age, BSA, gender and blood pressure, and Doppler aortic and pulmonary artery (PA) flow velocity measurements in 97 adults, aged 21 to 78 years, without clinical evidence of cardiac disease. No significant relationship was found between gender or blood pressure and aortic or PA flow velocity measurements. Aortic peak flow velocity, flow velocity integral, and average acceleration decreased with increasing age (all p less than 0.001), whereas ejection time (corrected for heart rate) increased, and acceleration time did not change. In contrast, there was no relationship between age and Doppler PA flow velocity measurements. Although there was no relationship between BSA and Doppler aortic flow measurements, PA peak flow velocity and average acceleration increased, while acceleration time decreased with increasing BSA (all p less than 0.02). Decreases in aortic peak flow velocity and flow velocity integral may be partly related to known increases in aortic root diameter with aging. The relationship between PA flow velocity measurements and BSA is not readily explained.
以往的研究表明，年龄和体表面积（BSA）与左心室、左心房和主动脉根部内径以及左心室壁厚度的M型超声心动图测量值之间存在关联。我们评估了97名年龄在21至78岁之间、无心脏病临床证据的成年人的年龄、BSA、性别与血压之间的关系，以及多普勒主动脉和肺动脉（PA）流速测量值之间的关系。未发现性别或血压与主动脉或PA流速测量值之间存在显著关系。主动脉峰值流速、流速积分和平均加速度随年龄增长而降低（所有p均小于0.001），而射血时间（经心率校正）增加，加速时间无变化。相比之下，年龄与多普勒PA流速测量值之间无关联。虽然BSA与多普勒主动脉血流测量值之间无关联，但PA峰值流速和平均加速度增加，而加速时间随BSA增加而降低（所有p均小于0.02）。主动脉峰值流速和流速积分的降低可能部分与已知的随着年龄增长主动脉根部直径增加有关。PA流速测量值与BSA之间的关系尚难以解释。
