Sagar K B, Wann L S, Boerboom L E, Kalbfleisch J, Rhyne T L, Olinger G N
Department of Medicine, Medical College of Wisconsin, Milwaukee 53226.
J Am Soc Echocardiogr. 1988 May-Jun;1(3):194-200. doi: 10.1016/s0894-7317(88)80075-0.
The purpose of this study was to determine the accuracy of Doppler-derived modal and maximum velocity and peak and mean acceleration of ascending aortic blood for the assessment of left ventricular systolic function. Studies were performed in six anesthetized open-chest dogs. Doppler-derived modal velocity, maximum velocity, and peak and mean acceleration were compared with left ventricular dP/dt, maximum aortic blood flow, and rate of blood flow measured with an electromagnetic flow probe under varying inotropic states. Maximum Doppler velocity showed better correlation (r = 0.94, y = 0.34 + 3.95) with maximum aortic blood flow than the modal velocity (r = 0.85, y = 1.49 + 3.85x). Peak acceleration also correlated better with the rate of blood flow (r = 0.92, y = 12.3 + 4.92x) than the mean acceleration (r = 0.83, y = 12.2 + 4.27x). Modal and maximum velocity and mean and peak acceleration correlated well with left ventricular dP/dt. We conclude that peak modal and peak maximum velocity and peak and mean acceleration are accurate measurements of left ventricular function. Maximum velocity and peak acceleration are more accurate than modal velocity and mean acceleration.
本研究的目的是确定经多普勒得出的升主动脉血流模态速度、最大速度、峰值加速度和平均加速度用于评估左心室收缩功能的准确性。对6只麻醉开胸犬进行了研究。在不同的变力状态下，将经多普勒得出的模态速度、最大速度、峰值加速度和平均加速度与左心室dp/dt、最大主动脉血流量以及用电磁血流探头测得的血流速率进行比较。与模态速度（r = 0.85，y = 1.49 + 3.85x）相比，最大多普勒速度与最大主动脉血流量的相关性更好（r = 0.94，y = 0.34 + 3.95）。峰值加速度与血流速率的相关性（r = 0.92，y = 12.3 + 4.92x）也比平均加速度（r = 0.83，y = 12.2 + 4.27x）更好。模态速度、最大速度以及平均加速度和峰值加速度与左心室dp/dt相关性良好。我们得出结论，峰值模态速度、峰值最大速度、峰值加速度和平均加速度是左心室功能的准确测量指标。最大速度和峰值加速度比模态速度和平均加速度更准确。
