Department of Chemistry and Biochemistry, Center for Electrochemistry, The University of Texas at Austin, 1 University Station, A5300, Austin, Texas 78712-0165, USA.
Anal Chem. 2012 Mar 6;84(5):2528-32. doi: 10.1021/ac203457h. Epub 2012 Feb 22.
We report a battery-powered, microelectrochemical sensing platform that reports its output using an electrochromic display. The platform is fabricated based on paper fluidics and uses a Prussian blue spot electrodeposited on an indium-doped tin oxide thin film as the electrochromic indicator. The integrated metal/air battery powers both the electrochemical sensor and the electrochromic read-out, which are in electrical contact via a paper reservoir. The sample activates the battery and the presence of analyte in the sample initiates the color change of the Prussian blue spot. The entire system is assembled on the lab bench, without the need for cleanroom facilities. The applicability of the device to point-of-care sensing is demonstrated by qualitative detection of 0.1 mM glucose and H(2)O(2) in artificial urine samples.
我们报告了一种电池供电的微电化学传感平台，该平台使用电致变色显示器报告其输出。该平台基于纸张流控技术构建，使用普鲁士蓝斑点作为电致变色指示剂，沉积在掺锡氧化铟薄膜上。集成的金属/空气电池为电化学传感器和电致变色读出器供电，它们通过纸张储液器保持电接触。样品激活电池，而样品中分析物的存在则引发普鲁士蓝斑点的颜色变化。整个系统在实验台上组装，无需使用洁净室设备。该设备在即时检测方面的适用性通过对人工尿液样本中 0.1 mM 葡萄糖和 H(2)O(2)的定性检测得到了证明。
