Section of Pulmonary, Allergy, Critical Care, and Sleep Medicine, University of Arizona College of Medicine, Tucson AZ.
Section of Pulmonary and Critical Care, Sleep Disorders Center, University of Chicago Pritzker School of Medicine, Chicago, IL.
Chest. 2012 Mar;141(3):798-808. doi: 10.1378/chest.11-1389.
Sleep-disordered breathing (SDB) comprises a diverse set of disorders marked by abnormal respiration during sleep. Clinicians should realize that SDB may present as acute cardiopulmonary failure in susceptible patients. In this review, we discuss three clinical phenotypes of acute cardiopulmonary failure from SDB: acute ventilatory failure, acute congestive heart failure, and sudden death. We review the pathophysiologic mechanisms and recommend general principles for management. Timely recognition of, and therapy for, SDB in the setting of acute cardiopulmonary failure may improve short- and long-term outcomes.
睡眠呼吸障碍(SDB)包括一组以睡眠期间呼吸异常为特征的不同疾病。临床医生应认识到,SDB 可能使易感患者发生急性心肺衰竭。在这篇综述中,我们讨论了 SDB 导致的三种急性心肺衰竭的临床表型:急性通气衰竭、急性充血性心力衰竭和猝死。我们回顾了病理生理机制并推荐了一般治疗原则。在急性心肺衰竭时及时识别和治疗 SDB 可能改善短期和长期结局。