Heshka S, Yang M U, Wang J, Burt P, Pi-Sunyer F X
Department of Medicine, St. Luke's-Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, New York, NY 10025.
Am J Clin Nutr. 1990 Dec;52(6):981-6. doi: 10.1093/ajcn/52.6.981.
The relation between change in resting metabolic rate (RMR) and change in fat-free mass (FFM) after weight loss is not well understood and is often inappropriately expressed in kilocalories per unit of FFM. We measured RMR and FFM in 35 obese patients enrolled in a conservative weight-loss program. RMR per kilogram FFM was not different after weight loss. However, the regression of delta RMR on delta FFM revealed that the decline in RMR tended to be greater than could be accounted for by loss of FFM. At initial test and retest, body fat (Fat) was not a predictor of RMR after FFM had been taken into account but delta Fat significantly contributed to the prediction of delta RMR when added to the equation after delta FFM. Thus, people losing larger amounts of weight had declines in RMR greater than could be accounted for by loss of FFM. Self-reported age of onset of obesity was not related to delta RMR.
减肥后静息代谢率（RMR）的变化与去脂体重（FFM）的变化之间的关系尚未得到充分理解，并且常以每单位FFM千卡数的形式被不恰当地表述。我们对35名参加保守减肥计划的肥胖患者测量了RMR和FFM。减肥后每千克FFM的RMR并无差异。然而，RMR变化量（delta RMR）对FFM变化量（delta FFM）的回归分析显示，RMR的下降趋势往往大于因FFM减少所能解释的程度。在初次测试和复测时，在考虑FFM后，体脂（Fat）并非RMR的预测指标，但当在delta FFM之后将delta Fat添加到方程中时，delta Fat对delta RMR的预测有显著贡献。因此，体重减轻较多的人RMR的下降幅度大于因FFM减少所能解释的程度。自我报告的肥胖发病年龄与delta RMR无关。
